monodeiodinationn.
/ˌmɒnə(ʊ)diːˈʌɪədᵻˌneɪʃn/, U.S. /ˈˌmɑnədiˌaɪədəˈneɪʃ(ə)n/ Biochemistry.
The removal of a single iodine atom from a compound; spec. the removal of an atom of iodine from the hormone thyroxine (tetraiodothyronine) to form triiodothyronine.
ΚΠ
1966 Endocrinology 78 302 (title) Hypothalamic influence of thyroxine monodeiodination by rat anterior pituitary gland.
1983 Endocrinology 113 1467/2 These changes are thought to represent an alteration in T4 monodeiodination, with decreased T3 production and preferential production of rT3 or an alteration in T4 and T4 clearance.
1992 Lancet 27 June 1575/1 All T4 is synthesized in the thyroid, whereas under normal circumstances 80% of plasma T3 is derived from 5′-monodeiodination of T4 in liver, kidney, and probably muscle.
This is a new entry (OED Third Edition, December 2002; most recently modified version published online March 2022).
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n.1966- ill-got
- ill-gotten
- ill-gotten goods never prosper
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