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单词 molindone
释义

molindonen.

Brit. /ˈmɒlɪndəʊn/, U.S. /ˈmɑlənˌdoʊn/
Origin: Formed within English, by derivation. Etymons: morpholine n., indole n., -one suffix.
Etymology: < m- and -ol- (in morpholine n.) + ind- (in indole n.; compare indo- comb. form2) + -one suffix.
Pharmacology.
An antipsychotic drug given orally (esp. as the hydrochloride) or intravenously; 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(morpholinomethyl)indol-4-one, C16H24N2O2.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > anti-psychotic tranquillizers
tranquillizer1800
thioxanthene1911
phenothiazine1940
piperoxan1950
fluphenazine1959
Melleril1959
thioridazine1959
methotrimeprazine1960
thiothixene1965
molindone1967
pimozide1968
risperidone1988
1967 Clin. Pharmacol. & Therapeutics 8 261 (heading) Molindone: an indole derivative with antipsychotic activity.
1976 J. R. Smythies & L. Corbett Psychiatry Students of Med. x. 194 Molindone (Moban) is a chemically new type of antischizophrenic compound.
1999 Jrnl. Clin. Psychiatry 60 Suppl. No. 21. 20 Weight gain has been reported with nearly every antipsychotic drug on the market (molindone is an exception).
This is a new entry (OED Third Edition, September 2002; most recently modified version published online March 2022).
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n.1967
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