1848 E. C. Gaskell I. vi. 90 (note) ‘I'm welly mithered’—I'm well nigh crazed.
a1973 J. R. R. Tolkien in C. Tolkien (1989) xvi. 334 Sam..stepped away, so sudden and grim was his master's face. ‘The poor dear is still mithered,’ he thought.
2001 18 Mar. (Life Suppl.) 10 Up all night trying to persuade his mithered wife to come to bed, he'd think of the lines from Lear.