mitogenn.
/ˈmʌɪtə(ʊ)dʒ(ə)n/, U.S. /ˈmaɪdədʒ(ə)n/ Cell Biology.
A substance or agent that stimulates mitosis (cell division), esp. in lymphocytes. Cf. mitogenic adj.
ΘΚΠ
the world > life > biology > biological processes > genetic activity > [noun] > cell-division or arrangement of chromosomes > substance promoting
mitogen1946
phytomitogen1961
1946 W. S. Bullough in Philos. Trans. (Royal Soc.) B. 231 511 It is therefore suggested that the term ‘mitogen’ be used to cover the whole group of mitosis-stimulating substances which exert their influence directly and not through an induced weakening of mitosis control.
1963 Proc. 9th Congr. European Soc. Haematol. II. i. 78 (heading) Factors stimulating cell division in cultured leucocytes. Chemical, serological and immunological studies on mitogens.
1971 Nature 31 Dec. 508/2 Pokeweed mitogen is one of the plant lectins which..can be used to stimulate lymphocytes in vitro.
1985 Proc. National Acad. Sci. U.S.A. 82 8044/1 The role of muscle growth factors in regeneration..is not known, but physiologically occurring mitogens may be involved.
2001 Res. Veterinary Sci. 70 115 Blood mononuclear cells from normal ponies proliferate when stimulated by mitogen (phytohaemagglutinin) or antigen.
This entry has been updated (OED Third Edition, June 2002; most recently modified version published online March 2022).
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n.1946