minigenen.

Brit.

/ˈmɪnɪdʒiːn/, U.S.

/ˈmɪniˌdʒin/

Origin: Formed within English, by compounding. Etymons: mini- comb. form, gene n.²

Etymology: < mini- comb. form + gene n.²

Genetics.

Originally: any of the genes coding for segments of the variable regions of immunoglobulin molecules. Later also: any short segment or artificially shortened version of a gene.

ΚΠ

1978 E. A. Kabat et al. in Proc. National Acad. Sci. U.S.A. 75 2431/2 There might well be intervening sequences between groups of FR [= framework] minigenes or even between minigenes.

1980 Science 25 Jan. 392/3 Gilbert suggests that gene fragments are not just random pieces of genes, but are themselves minigenes.

1991 Times 29 Aug. 5/1 A mini-gene has been engineered..that may pave the way for a treatment for Duchenne muscular dystrophy.

2001 Nucleic Acids Res. 29 886 Minigenes of TPO [= thrombopoietin] genomic constructs with variable exon-intron configurations or carrying exclusively the TPO cDNA were generated.

This is a new entry (OED Third Edition, March 2002; most recently modified version published online March 2022).

单词	minigene
释义	minigenen. Brit. /ˈmɪnɪdʒiːn/, U.S. /ˈmɪniˌdʒin/ Origin: Formed within English, by compounding. Etymons: mini- comb. form, gene n.² Etymology: < mini- comb. form + gene n.² Genetics. Originally: any of the genes coding for segments of the variable regions of immunoglobulin molecules. Later also: any short segment or artificially shortened version of a gene. ΚΠ 1978 E. A. Kabat et al. in Proc. National Acad. Sci. U.S.A. 75 2431/2 There might well be intervening sequences between groups of FR [= framework] minigenes or even between minigenes. 1980 Science 25 Jan. 392/3 Gilbert suggests that gene fragments are not just random pieces of genes, but are themselves minigenes. 1991 Times 29 Aug. 5/1 A mini-gene has been engineered..that may pave the way for a treatment for Duchenne muscular dystrophy. 2001 Nucleic Acids Res. 29 886 Minigenes of TPO [= thrombopoietin] genomic constructs with variable exon-intron configurations or carrying exclusively the TPO cDNA were generated. This is a new entry (OED Third Edition, March 2002; most recently modified version published online March 2022). < n.1978
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