单词 | mineralocorticoid |
释义 | mineralocorticoidn.adj. Physiology. A. n. Any steroid hormone produced by the adrenal cortex that acts to regulate salt and water balance in the body; esp. aldosterone. Also: any synthetic analogue of such a hormone. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > hormone > [noun] > other hormones thyro-iodine1896 parathormone1925 parathyroid hormone1925 oestrin1926 oestrogen1927 relaxin1930 theelin1930 prolan1931 galactin1932 inhibin1932 prolactin1932 oestriol1933 oestrone1933 oestradiol1934 adrenocorticotrophin1943 pancreozymin1943 ADH1945 adrenocorticotropin1945 cortisone1949 mineralocorticoid1950 electrocortin1953 aldosterone1954 angiotensin1958 melatonin1958 calcitonin1961 zeranol1971 amylin1988 adiponectin1999 adipokine2001 1950 H. Selye Physiol. & Pathol. Exposure to Stress 646 Mineralo-corticoids predispose to the formation of lung edema. 1964 L. C. Martin Clin. Endocrinol. (ed. 4) v. 165 The mineralocorticoids promote the retention of salt and water and the excretion of potassium by the renal tubules. 1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. vi. 12/2 Nowadays, the mineralocorticoid of choice in the treatment of defective secretion of endogenous aldosterone is the synthetic agent 9α-fluorocortisol. 1986 A. S. Romer & T. S. Parsons Vertebr. Body (ed. 6) xvii. 611 The other type, the mineralocorticoids, include 11-deoxycorticosterone and aldosterone; they increase the absorption of sodium and excretion of potassium by the kidneys. 2001 Clin. Pediatrics 40 125 The synthesis of other steroids such as mineralocorticoids and adrenal/gonadal sex steroids may also be affected [in congenital adrenal hyperplasia]. B. adj. Of, relating to, or designating such a hormone. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > hormone > [adjective] > of types of adipokinetic1947 paracrine1952 mineralocorticoid1954 1954 Science 19 Mar. 344/2 Electrocortin was yet the evasive mineralocorticoid spot on a paper chromatogram. 1965 New Scientist 1 July 33/1 The true mineralocorticoid hormone is aldosterone. 1981 R. N. Hardy Endocrine Physiol. ix. 114 The naturally occurring mineralocorticoid, aldosterone, possesses some 2000 times the mineralocorticoid activity of the glucocorticoids. 1990 Jrnl. Neuroendocrinol. 2 853/1 Receptors binding aldosterone with high affinity were termed type I or mineralocorticoid receptors. 1998 Proc. National Acad. Sci. U.S.A. 95 10200/1 Apparent mineralocorticoid excess is a genetic disorder that results in severe juvenile low-renin hypertension. This entry has been updated (OED Third Edition, March 2002; most recently modified version published online March 2022). < n.adj.1950 |
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