mifepristonen.
/mɪfɪˈprɪstəʊn/, U.S. /ˌmɪfəˈprɪsˌtoʊn/ Pharmacology.
A synthetic steroid that is a progesterone and glucocorticoid antagonist, used chiefly for the termination of early pregnancy (usually in combination with a prostaglandin) and as an emergency contraceptive; 11β-(4-dimethylaminophenyl)-17β-hydroxy-17α-prop-1-ynylestra-4,9-dien-3-one, C29H35NO2. Also called RU-486.
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RU-4861982
mifepristone1985
1985 Lancet 2 Nov. 1019/1 Mifepristone (RU486), a new steroid compound which antagonises progesterone and glucocorticosteroid action at the receptor level.
1990 Sci. Amer. June 18/1 Under the name mifepristone, RU 486 is administered as a tablet in conjunction with a small dose of a prostaglandin.
1993 Daily Tel. 18 Jan. 4/5 The French-made drug, mifepristone..can be used for women who are up to nine weeks pregnant.
1997 N.Y. Times 22 June xiv. 17/5 The much-awaited, much-contested Mifepristone, better known as RU-486, or the abortion pill, has been approved by the Food and Drug Administration.
This entry has been updated (OED Third Edition, March 2002; most recently modified version published online March 2022).
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n.1985