mexiletinen.

Brit.

/mᵻkˈsʌɪlətiːn/,

/mᵻkˈsɪlətiːn/, U.S.

/mɛkˈsɪlətin/

Origin: Formed within English, by compounding. Etymons: methyl n., English xil- , ethyl n., amine n.

Etymology: < me- (in methyl n.) + xil- (alteration of xyl- in xylyl n.) + et- (in ethyl n.) + -ine (in amine n.), after the alternative chemical name 1-methyl-2-(2,6-xylyloxy)ethylamine.

Pharmacology.

A drug with structure and actions similar to those of lidocaine, given (usually as the hydrochloride) orally or intravenously in the treatment of ventricular arrhythmias, and sometimes for the relief of neurogenic pain; 1-(2,6-dimethylphenoxy)-2-propanamine, C₆H₃(CH₃)₂(OCH₂CH(CH₃)NH₂).

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs

khellin1879

procainamide1950

pronethalol1963

propranolol1964

alprenolol1967

verapamil1967

oxprenolol1968

sotalol1968

perhexiline1969

practolol1969

beta-blocker1970

pindolol1971

acebutolol1972

mexiletine1973

atenolol1974

metoprolol1974

labetalol1975

propafenone1975

amrinone1977

1973 Jrnl. Pharmacy & Pharmacol. 25 July 550 (title) Spectrophotofluorometric and gas–liquid chromatographic methods for the estimation of mexiletine..in plasma and urine.

1980 Brit. Med. Jrnl. 18 Oct. 1072/3 A supraventricular tachycardia with aberrant conduction was mistaken for ventricular tachycardia and lignocaine was given without effect followed by mexiletine, which terminated it.

1984 Jrnl. Amer. College Cardiol. 4 48 The antiarrhythmic effects of the sustained release form of mexiletine (Mexitil-Perlongets) were evaluated.

1998 Movement Disorders 13 934 Oral mexiletine therapy may be a safe and effective treatment for spasmodic torticollis.

This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	mexiletine
释义	mexiletinen. Brit. /mᵻkˈsʌɪlətiːn/, /mᵻkˈsɪlətiːn/, U.S. /mɛkˈsɪlətin/ Origin: Formed within English, by compounding. Etymons: methyl n., English xil- , ethyl n., amine n. Etymology: < me- (in methyl n.) + xil- (alteration of xyl- in xylyl n.) + et- (in ethyl n.) + -ine (in amine n.), after the alternative chemical name 1-methyl-2-(2,6-xylyloxy)ethylamine. Pharmacology. A drug with structure and actions similar to those of lidocaine, given (usually as the hydrochloride) orally or intravenously in the treatment of ventricular arrhythmias, and sometimes for the relief of neurogenic pain; 1-(2,6-dimethylphenoxy)-2-propanamine, C₆H₃(CH₃)₂(OCH₂CH(CH₃)NH₂). ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs khellin1879 procainamide1950 pronethalol1963 propranolol1964 alprenolol1967 verapamil1967 oxprenolol1968 sotalol1968 perhexiline1969 practolol1969 beta-blocker1970 pindolol1971 acebutolol1972 mexiletine1973 atenolol1974 metoprolol1974 labetalol1975 propafenone1975 amrinone1977 1973 Jrnl. Pharmacy & Pharmacol. 25 July 550 (title) Spectrophotofluorometric and gas–liquid chromatographic methods for the estimation of mexiletine..in plasma and urine. 1980 Brit. Med. Jrnl. 18 Oct. 1072/3 A supraventricular tachycardia with aberrant conduction was mistaken for ventricular tachycardia and lignocaine was given without effect followed by mexiletine, which terminated it. 1984 Jrnl. Amer. College Cardiol. 4 48 The antiarrhythmic effects of the sustained release form of mexiletine (Mexitil-Perlongets) were evaluated. 1998 Movement Disorders 13 934 Oral mexiletine therapy may be a safe and effective treatment for spasmodic torticollis. This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1973
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