mevalonaten.

Brit.

/mᵻˈvaləneɪt/, U.S.

/məˈvæləˌneɪt/

Origin: Formed within English, by derivation. Etymons: mevalonic adj., -ate suffix¹.

Etymology: < mevalon- (in mevalonic adj.) + -ate suffix¹.

Biochemistry.

The anion of mevalonic acid, which is an intermediate in the biosynthesis of cholesterol and other steroids and terpenoids. Also: a salt or ester of mevalonic acid.

ΘΚΠ

the world > matter > chemistry > chemical substances > acids > [noun] > acid radicals

persulphate1813

suberyl1836

nitrion1868

stearyl1868

nitroxyl1871

nitro group1877

haloacyl1951

mevalonate1957

1957 Biochimica et Biophysica Acta 26 212 During the course of certain studies in metabolism it became necessary to differentiate mevalonate from acetate.

1959 A. White et al. Princ. Biochem. (ed. 2) xix. 488 Mevalonic kinase..catalyzes the formation of phosphomevalonic acid and ADP from mevalonate and ATP.

1971 K. Hunter & A. H. Rose in A. H. Rose & J. S. Harrison Yeasts II. vi. 243 Brewer's solubles were shown to contain a compound which could replace acetate in sterol biosynthesis, and this compound was shown to be mevalonate.

1988 L. Stryer Biochem. (ed. 3) xxiii. 555 It was found that mevalonate could substitute for acetate to meet the nutritional needs of acetate-requiring mutants.

2000 Jrnl. Cell Biol. 148 915 The integral ER membrane protein HMG-CoA reductase is a key enzyme of the mevalonate pathway from which sterols and other essential molecules are produced.

This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	mevalonate
释义	mevalonaten. Brit. /mᵻˈvaləneɪt/, U.S. /məˈvæləˌneɪt/ Origin: Formed within English, by derivation. Etymons: mevalonic adj., -ate suffix¹. Etymology: < mevalon- (in mevalonic adj.) + -ate suffix¹. Biochemistry. The anion of mevalonic acid, which is an intermediate in the biosynthesis of cholesterol and other steroids and terpenoids. Also: a salt or ester of mevalonic acid. ΘΚΠ the world > matter > chemistry > chemical substances > acids > [noun] > acid radicals persulphate1813 suberyl1836 nitrion1868 stearyl1868 nitroxyl1871 nitro group1877 haloacyl1951 mevalonate1957 1957 Biochimica et Biophysica Acta 26 212 During the course of certain studies in metabolism it became necessary to differentiate mevalonate from acetate. 1959 A. White et al. Princ. Biochem. (ed. 2) xix. 488 Mevalonic kinase..catalyzes the formation of phosphomevalonic acid and ADP from mevalonate and ATP. 1971 K. Hunter & A. H. Rose in A. H. Rose & J. S. Harrison Yeasts II. vi. 243 Brewer's solubles were shown to contain a compound which could replace acetate in sterol biosynthesis, and this compound was shown to be mevalonate. 1988 L. Stryer Biochem. (ed. 3) xxiii. 555 It was found that mevalonate could substitute for acetate to meet the nutritional needs of acetate-requiring mutants. 2000 Jrnl. Cell Biol. 148 915 The integral ER membrane protein HMG-CoA reductase is a key enzyme of the mevalonate pathway from which sterols and other essential molecules are produced. This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1957
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