methylasen.

Brit.

/ˈmɛθᵻleɪz/, U.S.

/ˈmɛθəˌleɪz/

Origin: Formed within English, by derivation. Etymons: methyl n., -ase suffix.

Etymology: < methyl n. + -ase suffix. Compare slightly earlier methyltransferase n. and hydroxymethylase ( < hydroxymethyl n. at hydroxy- comb. form 3 + -ase suffix):1958 Science 18 July 121/1 Serine hydroxymethylase.

Biochemistry.

= methyltransferase n.DNA methylase: see DNA n. Compounds 1.

ΚΠ

1962 E. Fleissner & E. Borek in Proc. National Acad. Sci. U.S.A. 48 1202 It is apparent from these data that a soluble enzyme, RNA methylase, exists in E. coli which can methylate the base components of soluble RNA when the latter are already in some polynucleotide form.

1969 New Scientist 13 Nov. 329/1 It has been known for some time that certain bases in bacterial DNA are methylated, probably immediately after replication... The group of enzymes—methylases—responsible for these reactions have been isolated from several bacterial species.

1982 European Jrnl. Biochem. 128 349 Protein methylase II (S-adenosylmethionine: protein-carboxyl O-methyltransferase, EC 2.1.1.24) was purified from wheat germ.

1990 Nucleic Acids Res. 18 274/1 Earlier we have used sequence specific methylases as probes for altered conformations in form V DNA.

2000 Biochem. & Biophysical Res. Communications 270 46 The endonuclease as well as the methylase were found to be associated with the cytoplasmic membrane.

This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	methylase
释义	methylasen. Brit. /ˈmɛθᵻleɪz/, U.S. /ˈmɛθəˌleɪz/ Origin: Formed within English, by derivation. Etymons: methyl n., -ase suffix. Etymology: < methyl n. + -ase suffix. Compare slightly earlier methyltransferase n. and hydroxymethylase ( < hydroxymethyl n. at hydroxy- comb. form 3 + -ase suffix):1958 Science 18 July 121/1 Serine hydroxymethylase. Biochemistry. = methyltransferase n.DNA methylase: see DNA n. Compounds 1. ΚΠ 1962 E. Fleissner & E. Borek in Proc. National Acad. Sci. U.S.A. 48 1202 It is apparent from these data that a soluble enzyme, RNA methylase, exists in E. coli which can methylate the base components of soluble RNA when the latter are already in some polynucleotide form. 1969 New Scientist 13 Nov. 329/1 It has been known for some time that certain bases in bacterial DNA are methylated, probably immediately after replication... The group of enzymes—methylases—responsible for these reactions have been isolated from several bacterial species. 1982 European Jrnl. Biochem. 128 349 Protein methylase II (S-adenosylmethionine: protein-carboxyl O-methyltransferase, EC 2.1.1.24) was purified from wheat germ. 1990 Nucleic Acids Res. 18 274/1 Earlier we have used sequence specific methylases as probes for altered conformations in form V DNA. 2000 Biochem. & Biophysical Res. Communications 270 46 The endonuclease as well as the methylase were found to be associated with the cytoplasmic membrane. This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1962
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