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单词 metabolite
释义

metaboliten.

Brit. /mᵻˈtabəlʌɪt/, /mɛˈtabəlʌɪt/, U.S. /məˈtæbəˌlaɪt/
Origin: Formed within English, by derivation. Etymons: metabolism n., -ite suffix1.
Etymology: < metabol- (in metabolism n.) + -ite suffix1.
Biology and Biochemistry.
A substance that is a substrate or product of a metabolic reaction, or that is necessary to a metabolic reaction; esp. an intermediate or end product of a metabolic pathway.
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the world > life > biology > substance > process stimulators or inhibitors > metabolite > [noun]
metabolite1877
1877 M. Foster Text Bk. Physiol. App. 531 Nitrogenous metabolites: the urea group, amides, and similar bodies.
1882 S. H. Vines tr. J. von Sachs Text-bk. Bot. (ed. 2) i. 62 The products of metabolic transformations have been conveniently termed by Foster ‘metabolites’.
1890 J. Cagney tr. R. von Jaksch Clin. Diagnosis vi. 169 Certain colourless metabolites of bilirubin.
1923 Jrnl. Physiol. 57 248 The increased combustion of sugar is immediately followed by the physiological oxidation of the accumulated fatty acid metabolites.
1946 P. H. Mitchell Textbk. Biochem. xii. 322 The modern view of typical cases of biological oxidation is that enzymes catalyze the transfer of H2 from a fuel food (the metabolite) to another substance.
1951 M. Abercrombie et al. Dict. Biol. 159 Most metabolites are made by the organism in the course of metabolism; others must be taken in from the environment... Autotrophic organisms need to take in only inorganic metabolites, e.g. water, carbon dioxide, nitrates... Heterotrophic organisms need..a wide range of organic metabolites from the environment.
1965 J. Lee & F. Knowles Animal Hormones iv. 76 Progesterone appears to be an intermediary metabolite in the formation of adrenal cortical hormones.
1970 G. R. Taylor Doomsday Bk. vi. 130 In the body..DDT tends to convert into similar substances known as DDE and DDD, the three being known..as ‘DDT and its metabolites’.
1987 Greyhound Star Sept. 30/2 The blood also transports metabolites, such as waste nitrogenous compounds, and acids from muscles after exercise.
1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. lix. 224 The antimetabolites are structural analogues of normal metabolites required for cell function and replication.
This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).
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n.1877
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