单词 | mianserin |
释义 | mianserinn. Pharmacology. A tetracyclic antidepressant with sedative effects, given orally as the hydrochloride; 1,2,3,4,10,14b-hexahydro-2-methyldibenzo[c,f]pyrazino[1,2a]azepine, C18H20N2. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs Marsilid1952 iproniazid1953 levallorphan1953 imipramine1958 Tofranil1958 isocarboxazid1959 Marplan1959 Nardil1959 nialamide1959 Niamid1959 phenelzine1959 tranylcypromine1959 Parnate1960 amitriptyline1961 monoamine oxidase inhibitor1962 nortriptyline1962 protriptyline1963 MAOI1965 maprotiline1970 mianserin1970 amoxapine1971 fluoxetine1975 paroxetine1977 Prozac1985 Seroxat1985 1970 Jrnl. Medicinal Chem. 13 36/1 Compound 5 (mianserin) proved to have..a less pronounced sedative effect and a lower acute toxicity as shown in pilot experiments on animals. 1986 C. W. Thornber in C. A. Heaton Chem. Industry iv. 189 Further chemical modifications have led to variants such as mianserin..which has additional properties as a serotonin antagonist. 1989 New Scientist 18 Mar. 31/2 The Committee on Safety of Medicines..declared that doctors' reports of adverse reactions in the blood to the antidepressant drug mianserin (Bolvidon) confirmed its own earlier warnings that the elderly are abnormally susceptible to these reactions. 1998 European Neuropsychopharmacol. 8 297 The antinociceptive effects of the tetracyclic antidepressant mianserin and its interaction with various opioid receptor subtypes was evaluated. This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1970 |
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