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单词 mepyramine
释义

mepyraminen.

Brit. /mᵻˈpɪrəmiːn/, /mᵻˈpʌɪrəmiːn/, U.S. /məˈpɪrəˌmin/, /məˈpɪrəm(ə)n/
Origin: Formed within English, by compounding. Etymons: methyl n., pyridine n., amine n.
Etymology: < me- (in methyl n.) + pyr- (in pyridine n.) + amine n.
Pharmacology.
A polycyclic substituted amine, C17H23N3O, with antihistamine properties, used in treating allergic conditions.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > antihistamine medicines > [noun]
pyribenzamine1946
diphenhydramine1947
tripelennamine1947
mepyramine1949
anti-histaminic1950
meclozine1955
triprolidine1956
antihistamine1957
trimeprazine1959
methapyrilene1974
1949 Lancet 9 July 47/2 The histamine antagonist, N(2-dimethylaminoethyl)N(p-methoxybenzyl)2-aminopyridine maleate..later known on the continent as ‘Neoantergan’ and in this country as ‘Anthisan’ or mepyramine maleate..was soon recognised as the most powerful and specific of the histamine antagonists.
1964 W. G. Smith Allergy & Tissue Metabolism v. 61 One of these was histamine whose actions could be blocked by mepyramine.
1972 Nature 21 Apr. 369/1 Certain responses..are not antagonized by the classical antihistaminic drugs, such as mepyramine.
1987 G. G. Lunt in A. J. Turner & H. S. Bachelard Neurochemistry v. 148 Bielkiwicz and Cook..reported the specific, high affinity binding of the histamine receptor ligand, mepyramine, to glass fibre filters.
This entry has been updated (OED Third Edition, September 2001; most recently modified version published online March 2022).
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n.1949
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