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单词 meprobamate
释义

meprobamaten.

Brit. /mᵻˈprəʊbəmeɪt/, /ˌmɛprəˈbameɪt/, U.S. /məˈproʊbəˌmeɪt/, /ˌmɛprəˈbæˌmeɪt/
Origin: Formed within English, by compounding. Etymons: methyl n., propyl n., carbamate n. at carbamide n. Derivatives.
Etymology: < me- (in methyl n.) + pro- (in propyl n.) + -bamate (in carbamate n. at carbamide n. Derivatives).
Pharmacology.
A carbamate compound with sedative properties, used chiefly in the treatment of anxiety disorders and as a muscle relaxant; 2-methyl-2-propyl-1,3-propanediol dicarbamate, C9H18N2O4.Proprietary names for this drug include Miltown and Equanil.As an anxiolytic, this drug has now been largely superseded by the benzodiazepines, in part because of their somewhat lower risk of problems with dependence.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > tranquillizer > specific substances or preparations
nepenthes1580
nepenthe1595
Seconal1935
secobarbital1950
mephenesin1952
Largactil1953
Miltown1954
meprobamate1955
hydroxyzine1956
promazine1956
Sparine1956
prochlorperazine1957
Stelazine1958
trifluoperazine1958
Prolixin1959
chlordiazepoxide1960
Librium1960
diazepam1961
Valium1961
oxazepam1964
pimozide1968
lorazepam1969
temazepam1970
alprazolam1973
1955 Dispensatory U.S.A. (ed. 25) 1861/1 Meprobamate. Equanil (Wyeth). Miltown (Wallace).—This is 2-methyl-2-n-propyl-1,3-propanediol dicarbamate.
1962 A. Huxley Island xiii. 201 Mass opiates in the form of television, meprobamate, positive thinking and cigarettes.
1965 Evening Standard 13 Sept. 10/3 He had an envelope full of pep pills—amphetamine—in his left coat pocket and an envelope full of Equanils—meprobamate—in his right pocket.
1977 J. F. Fixx Compl. Bk. Running ii. 17 The researchers tested the volunteers after 400-milligram doses of meprobamate, a widely used tranquilizer.
1992 Discover Feb. 84/3 Withdrawal from meprobamate was the likely source of Mrs. Morris's delusions.
This entry has been updated (OED Third Edition, September 2001; most recently modified version published online March 2022).
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n.1955
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