methsuximiden.

Brit.

/mɛθˈsʌksəmʌɪd/, U.S.

/mɛθˈsəksəˌmaɪd/

Origin: Formed within English, by compounding. Etymons: methyl n., ethosuximide n.

Etymology: < meth- (in methyl n.: see note s.v. meth- comb. form) + -suximide (in ethosuximide n.).

Pharmacology.

An anticonvulsant drug similar to but somewhat more toxic than ethosuximide, used chiefly for the treatment of refractory absence and myoclonic seizures; N,2-dimethyl-2-phenylsuccinimide, C₁₂H₁₃NO₂.International Nonproprietary Name (1996): mesuximide.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations

Dilantin1938

phenytoin1942

Artane1948

Mysoline1949

mephenesin1952

troxidone1952

primidone1953

acetazolamide1954

orphenadrine1957

tetrabenazine1958

ethosuximide1960

methsuximide1965

clonazepam1970

valproic1972

valproate1974

1965 National Formulary (Amer. Pharm. Assoc.) (ed. 12) 258/1 Methsuximide..contains not less than 97 per cent and not more than 103 per cent of C₁₂H₁₃NO₂ calculated on the dried basis.

1967 Martindale's Extra Pharmacopoeia (ed. 25) 1082/1 In about one-third of the patients given methsuximide, minor side-effects occur which include anorexia, nausea, vomiting, constipation..and ataxia.

1972 R. White Be not Afraid xvi. 190 Celontin (or methsuximide) is billed as an anticonvulsant.

1996 Seizure 5 47 Methsuximide monotherapy as demonstrated in these five patients is an effective treatment for JME [= juvenile myoclonic epilepsy].

This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	methsuximide
释义	methsuximiden. Brit. /mɛθˈsʌksəmʌɪd/, U.S. /mɛθˈsəksəˌmaɪd/ Origin: Formed within English, by compounding. Etymons: methyl n., ethosuximide n. Etymology: < meth- (in methyl n.: see note s.v. meth- comb. form) + -suximide (in ethosuximide n.). Pharmacology. An anticonvulsant drug similar to but somewhat more toxic than ethosuximide, used chiefly for the treatment of refractory absence and myoclonic seizures; N,2-dimethyl-2-phenylsuccinimide, C₁₂H₁₃NO₂.International Nonproprietary Name (1996): mesuximide. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations Dilantin1938 phenytoin1942 Artane1948 Mysoline1949 mephenesin1952 troxidone1952 primidone1953 acetazolamide1954 orphenadrine1957 tetrabenazine1958 ethosuximide1960 methsuximide1965 clonazepam1970 valproic1972 valproate1974 1965 National Formulary (Amer. Pharm. Assoc.) (ed. 12) 258/1 Methsuximide..contains not less than 97 per cent and not more than 103 per cent of C₁₂H₁₃NO₂ calculated on the dried basis. 1967 Martindale's Extra Pharmacopoeia (ed. 25) 1082/1 In about one-third of the patients given methsuximide, minor side-effects occur which include anorexia, nausea, vomiting, constipation..and ataxia. 1972 R. White Be not Afraid xvi. 190 Celontin (or methsuximide) is billed as an anticonvulsant. 1996 Seizure 5 47 Methsuximide monotherapy as demonstrated in these five patients is an effective treatment for JME [= juvenile myoclonic epilepsy]. This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1965
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