单词 | menadione |
释义 | menadionen. Pharmacology (originally U.S.). A yellow crystalline powder, C11H8O2, which is a synthetic derivative of naphthoquinone and is used, usually in the form of its sodium bisulphite (sodium sulphonate) derivative, to treat haemorrhage by stimulating the production of prothrombin; 2-methyl-1, 4-naphthoquinone. Also called menaphthone. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > astringent or restringent preparations > [noun] > for stopping bleeding > synthetic hydrastinine1887 menadione1941 menaphthone1943 tranexamic acid1968 1941 Jrnl. Amer. Med. Assoc. 15 Mar. 1054/1 The Council has adopted the term ‘menadione’..and has authorized its use as a nonproprietary name to describe the substance 2-methyl-1, 4-naphthoquinone. 1942 T. Sollmann Man. Pharmacol. (ed. 6) 496 Various other naphthoquinone derivatives have the same action, for instance..‘menadione’, N.N.R. (menaquinone),..which is three or four times more potent than the K vitamin. 1955 J. G. Davis Dict. Dairying (ed. 2) 566 It has been claimed that feeding menadione..to lactating cows will increase the keeping quality of the milk. 1968 J. H. Burn Lect. Notes Pharmacol. (ed. 9) 83 Menaphthone (menadione or methylnaphthoquinone) is a substance which..increases the production of prothrombin in those deficient. It is commonly given to mothers a day or two before the baby is born. 1988 BioFactors 1 57/1 Early studies clearly demonstrated that menadione was not a substrate for the enzyme. This entry has been updated (OED Third Edition, September 2001; most recently modified version published online March 2022). < |
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