methenaminen.
/mᵻˈθiːnəmiːn/, /mᵻˈθiːnəmɪn/, U.S. /məˈθɛnəm(ə)n/, /məˈθɛnəˌmin/ 1. Chiefly Pharmacology. The compound hexamethylenetetramine, (CH2)6N4, or a derivative of this (often with mandelic acid), esp. when used as a urinary antiseptic.Hexamine is the preferred name in the British Pharmacopoeia.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > antiseptic > [noun] > specific
naphthalene1821
carbolic acid1835
creosote1835
Sanitas1878
chlorocresol1886
salol1887
Listerine1889
salufer1894
Airol1895
fluorol1895
thymoform1899
xeroform1901
triformol1907
thymoloform1911
hexamine1914
Eusol1915
flavine1917
proflavine1917
Dakin1920
naphtha1920
methenamine1926
T.C.P.1934
Zephiran1935
leptazol1946
cetrimide1948
nalidixic acid1962
clioquinol1967
crystal violet1996
1926 Pharmacopeia U.S. 238 Methenamine.
1926 Dispensatory U.S.A. (ed. 21) 695/2 Not only are there a large number of compounds of methenamine upon the market, but the official drug is sold under an almost innumerable number of trade names.
1948 E. Pound Pisan Cantos lxxiv. 12 Methenamine eases the urine.
1951 A. Grollman Pharmacol. & Therapeutics xxv. 526 Hexamethylenetetramine ((CH2)6N4), official as methenamine (U.S.P.) and hexamine (B.P.)..is of interest from its liberating formaldehyde in the course of its excretion in the urine.
1969 J. H. Thompson in J. A. Bevan Essent. Pharmacol. xlix. 511 Methenamine mandelate is a mixture of methenamine and mandelic acid.., two old urinary antiseptic agents which today are rarely given separately.
1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) vi. 102 Nitrofurantoin..and methenamine. These agents are used mainly to prevent recurrent urinary tract infections.
1998 Jrnl. Pharmacol. & Biomed. Anal. 16 939 A capillary gas chromatographic method is described for the determination of methenamine hippurate residue in swabs collected from manufacturing equipment surfaces.
2. Pathology. In full methenamine silver. A solution of methenamine and silver nitrate, used in several histological stains. Frequently attributive.
ΚΠ
1952 G. Gomori Microsc. Histochem. vii. 60 Methenamine-silver is practically free from these drawbacks.
1953 Jrnl. Histochem. & Cytochem. 1 391 The mounted sections were treated with one of the oxidants, then stained for aldehydes with Gomori's methenamine-silver (pH 8.4).
1967 Canad. Med. Assoc. Jrnl. 97 4/1 The organism can be identified in pathologic material only by means of methenamine-silver stains.
1977 Ann. Internal Med. 86 586/2 Sections stained with methenamine-silver showed many yeast forms consistent with H. capsulatum.
1991 Acta Neuropathologica 81 540/2 We recently developed a new type of methenamine silver stain for detecting SP [senile plaques].
1999 Internat. Jrnl. Urol. 6 111 Postoperatively, periodic acid-Schiff and Grocott-Gomori methenamine tests revealed Actinomyces.
This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).
<
n.1926