mefenamicadj.

Brit.

/mɛfəˈnamɪk/, U.S.

/ˌmɛfəˈnæmɪk/

Origin: Formed within English, by derivation. Etymons: methyl n., phen- comb. form, amino- comb. form, -ic suffix.

Etymology: < me- (in methyl n.) + fen- (alteration of phen- comb. form) + am- (in amino- comb. form) + -ic suffix.

Pharmacology.

mefenamic acid n. a drug which inhibits prostaglandin synthesis and is used as an anti-inflammatory agent and analgesic; 2-[(2,3-dimethylphenyl)amino]benzoic acid, C₁₅H₁₅NO₂.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations allaying inflammation > [noun] > synthetic or biological

hydroxycorticosterone1943

hydrocortisone1951

cortisol1953

prednisolone1955

prednisone1955

triamcinolone1957

mefenamic acid1962

ibuprofen1967

tetracosactrin1967

the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics

Hoffmann's anodyne1747

acetylsalicylic acid1873

acetophenetidin1888

exalgin1889

pyramidon1898

aspirin1899

phenazone1899

Veganin1926

Trilene1935

Demerol1940

pethidine1942

Tridione1944

amidone1946

meperidine1947

methadone1947

Physeptone1947

Butazolidin1951

phenylbutazone1952

opioid1955

Panadol1955

propoxyphene1955

Tylenol1956

acetaminophen1957

paracetamol1957

Distalgesic1958

oxycodone1958

Sernyl1958

morphinomimetic1959

phencyclidine1959

levorphanol1960

mefenamic acid1962

pentazocine1964

Talwin1965

ibuprofen1967

nalbuphine1969

naproxen1971

phy1971

Nurofen1982

1962 Jrnl. Pharmacol. & Exper. Therapeutics 138 405/1 N-(2,3-xylyl)anthranilic acid (CI-473; mefenamic acid), prepared by the copper-catalyzed condensation of o-chlorobenzoic acid and 2,3-dimethylaniline, has a molecular weight of 241.3.

1967 New Scientist 27 Apr. 217/3 Anti-inflammatory drugs such as phenylbutazone, mefenamic acid and flufenamic acid.

1987 M. J. Neal Med. Pharmacol. at Glance xxviii. 63/2 Fenamates (e.g. mefenamic acid) have the disadvantage of causing diarrhoea.

1997 Daily Tel. 25 Feb. 16/3 Some hysterectomies might be avoided with the careful use of such drugs as tranexamic acid (Cyklokapron) or mefenamic acid (Ponstan).

This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022).

单词	mefenamic
释义	mefenamicadj. Brit. /mɛfəˈnamɪk/, U.S. /ˌmɛfəˈnæmɪk/ Origin: Formed within English, by derivation. Etymons: methyl n., phen- comb. form, amino- comb. form, -ic suffix. Etymology: < me- (in methyl n.) + fen- (alteration of phen- comb. form) + am- (in amino- comb. form) + -ic suffix. Pharmacology. mefenamic acid n. a drug which inhibits prostaglandin synthesis and is used as an anti-inflammatory agent and analgesic; 2-[(2,3-dimethylphenyl)amino]benzoic acid, C₁₅H₁₅NO₂. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations allaying inflammation > [noun] > synthetic or biological hydroxycorticosterone1943 hydrocortisone1951 cortisol1953 prednisolone1955 prednisone1955 triamcinolone1957 mefenamic acid1962 ibuprofen1967 tetracosactrin1967 the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics Hoffmann's anodyne1747 acetylsalicylic acid1873 acetophenetidin1888 exalgin1889 pyramidon1898 aspirin1899 phenazone1899 Veganin1926 Trilene1935 Demerol1940 pethidine1942 Tridione1944 amidone1946 meperidine1947 methadone1947 Physeptone1947 Butazolidin1951 phenylbutazone1952 opioid1955 Panadol1955 propoxyphene1955 Tylenol1956 acetaminophen1957 paracetamol1957 Distalgesic1958 oxycodone1958 Sernyl1958 morphinomimetic1959 phencyclidine1959 levorphanol1960 mefenamic acid1962 pentazocine1964 Talwin1965 ibuprofen1967 nalbuphine1969 naproxen1971 phy1971 Nurofen1982 1962 Jrnl. Pharmacol. & Exper. Therapeutics 138 405/1 N-(2,3-xylyl)anthranilic acid (CI-473; mefenamic acid), prepared by the copper-catalyzed condensation of o-chlorobenzoic acid and 2,3-dimethylaniline, has a molecular weight of 241.3. 1967 New Scientist 27 Apr. 217/3 Anti-inflammatory drugs such as phenylbutazone, mefenamic acid and flufenamic acid. 1987 M. J. Neal Med. Pharmacol. at Glance xxviii. 63/2 Fenamates (e.g. mefenamic acid) have the disadvantage of causing diarrhoea. 1997 Daily Tel. 25 Feb. 16/3 Some hysterectomies might be avoided with the careful use of such drugs as tranexamic acid (Cyklokapron) or mefenamic acid (Ponstan). This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022). < adj.1962
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