melanosisn.

Brit.

/ˌmɛləˈnəʊsɪs/, U.S.

/ˌmɛləˈnoʊsəs/

Inflections: Plural melanoses Brit.

/ˌmɛləˈnəʊsiːz/, U.S.

/ˌmɛləˈnoʊsiz/.

Origin: A borrowing from Greek, combined with an English element; modelled on a French lexical item. Etymons: Greek μελαν- , μέλας , -osis suffix.

Etymology: < ancient Greek μελαν-, μέλας black (see melano- comb. form) + -osis suffix, after French mélanose melanose n. Compare Hellenistic Greek μελάνωσις process of becoming black.

Medicine.

1. Originally: any of various conditions marked by abnormal black or dark brown pigmentation of one or more organs or tissues of the body. Now: spec. any of several conditions characterized by the presence of excessive melanin or of melanocytic lesions in the skin or elsewhere in the body. Also: a benign or premalignant melanocytic lesion (now rare).Use of the word for conditions involving pigments or materials other than melanin survives only in sense 3.

ΘΚΠ

the world > health and disease > ill health > a disease > diseases of tissue > [noun] > abnormal pigmentation

melanosis1821

ochronosis1867

polychromia1897

the world > health and disease > ill health > a disease > disorders of visible parts > skin disorders > [noun] > disordered pigmentation > patch of

melanosis1821

melanose1829

chloasma1877

age spot1890

lentigo1894

lentigo maligna1954

1821 J. Forbes tr. R. T. H. Laennec Treat. Dis. Chest i. i. ix. 124 (heading) Of melanosis of the lungs.

1823 Trans. Med.-Chir. Soc. Edinb. (1824) 264 We observed in a horse the disease termed Melanosis, developed to a remarkable degree.

1829 S. Cooper Good's Study Med. (ed. 3) III. 341 In the cutaneous texture, says Breschet, melanoses are common.

1843 R. J. Graves Syst. Clin. Med. xxx. 382 In some whites this tendency to secrete black matter becomes excessive, and gives rise to certain forms of melanosis.

1899 T. C. Allbutt et al. Syst. Med. VIII. 700 Freckles may be considered as actinic melanoses.

1953 M. Gordon Pigment Cell Growth 327 A useful oral preparation for treating the hyperpigmentation of chloasma and Riehl's melanosis may be parahydroxypropiophenone.

1967 Canad. Med. Assoc. Jrnl. 97 12/2 The melanoma developed from Dubreuilh's precancerous melanosis (lenigo maligna, Hutchinson freckle) has a slower rate of growth, metastasis and invasiveness.

1999 Internat. Jrnl. Gynecol. Pathol. 18 73 Two cases of cervical melanosis, an uncommon process characterized by hyperpigmentation of the basal epithelium, with or without accompanying basal melanocytes, are reported.

†2. Malignant melanoma. Obsolete.

ΘΚΠ

the world > health and disease > ill health > a disease > diseases of tissue > [noun] > cancer > types of

soft cancer1804

soot-wart?1810

melanosis1826

mastoid cancer1846

skin cancer1847

cancroid1854

epithelioma1872

soot-cancer1878

scirrhus1881

chimney-sweep's cancer1888

peau d'orange1896

pigskin1898

medullary carcinoma1926

1826 Lancet 1 Apr. 19/2 The tumour presented all the characters of the cancerous melanosis.

1834 J. Forbes tr. R. T. H. Laennec Treat. Dis. Chest (ed. 4) 355 Melanosis is one of the rarest species of cancer.

1877 F. T. Roberts Handbk. Med. (ed. 3) I. 277 Melanosis and colloid are generally regarded as forms of cancer .

3. Brown or black discoloration of the mucous membrane of a part of the intestinal tract, esp. the colon, often associated with excessive consumption of anthraquinone laxatives. Chiefly in melanosis coli.

ΚΠ

1931 Jrnl. Pathol. & Bacteriol. 34 61 At that time [sc. 1847] Virchow did not coin a special name for the condition but in 1858 he provided a specimen, now in the museum of the Pathological Institute at Berlin, labelled in his own hand-writing ‘melanosis coli’.

1931 Jrnl. Pathol. & Bacteriol. 34 62 The first detailed account of the morbid anatomy of melanosis coli was given by Pick in 1911... Pick adopted the term melanosis coli without being aware of its previous use by Virchow.

1982 Jrnl. Submicrosc. Cytol. 14 389 The pigment in melanosis duodeni resides in the lysosomes of macrophages in the lamina propria.

1992 Carcinogenesis 13 2217 Morphological observation of the intestines also revealed melanosis, crypt abscesses and erosion, becoming more pronounced with length of exposure to the anthraquinone.

This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022).

单词	melanosis
释义	melanosisn. Brit. /ˌmɛləˈnəʊsɪs/, U.S. /ˌmɛləˈnoʊsəs/ Inflections: Plural melanoses Brit. /ˌmɛləˈnəʊsiːz/, U.S. /ˌmɛləˈnoʊsiz/. Origin: A borrowing from Greek, combined with an English element; modelled on a French lexical item. Etymons: Greek μελαν- , μέλας , -osis suffix. Etymology: < ancient Greek μελαν-, μέλας black (see melano- comb. form) + -osis suffix, after French mélanose melanose n. Compare Hellenistic Greek μελάνωσις process of becoming black. Medicine. 1. Originally: any of various conditions marked by abnormal black or dark brown pigmentation of one or more organs or tissues of the body. Now: spec. any of several conditions characterized by the presence of excessive melanin or of melanocytic lesions in the skin or elsewhere in the body. Also: a benign or premalignant melanocytic lesion (now rare).Use of the word for conditions involving pigments or materials other than melanin survives only in sense 3. ΘΚΠ the world > health and disease > ill health > a disease > diseases of tissue > [noun] > abnormal pigmentation melanosis1821 ochronosis1867 polychromia1897 the world > health and disease > ill health > a disease > disorders of visible parts > skin disorders > [noun] > disordered pigmentation > patch of melanosis1821 melanose1829 chloasma1877 age spot1890 lentigo1894 lentigo maligna1954 1821 J. Forbes tr. R. T. H. Laennec Treat. Dis. Chest i. i. ix. 124 (heading) Of melanosis of the lungs. 1823 Trans. Med.-Chir. Soc. Edinb. (1824) 264 We observed in a horse the disease termed Melanosis, developed to a remarkable degree. 1829 S. Cooper Good's Study Med. (ed. 3) III. 341 In the cutaneous texture, says Breschet, melanoses are common. 1843 R. J. Graves Syst. Clin. Med. xxx. 382 In some whites this tendency to secrete black matter becomes excessive, and gives rise to certain forms of melanosis. 1899 T. C. Allbutt et al. Syst. Med. VIII. 700 Freckles may be considered as actinic melanoses. 1953 M. Gordon Pigment Cell Growth 327 A useful oral preparation for treating the hyperpigmentation of chloasma and Riehl's melanosis may be parahydroxypropiophenone. 1967 Canad. Med. Assoc. Jrnl. 97 12/2 The melanoma developed from Dubreuilh's precancerous melanosis (lenigo maligna, Hutchinson freckle) has a slower rate of growth, metastasis and invasiveness. 1999 Internat. Jrnl. Gynecol. Pathol. 18 73 Two cases of cervical melanosis, an uncommon process characterized by hyperpigmentation of the basal epithelium, with or without accompanying basal melanocytes, are reported. †2. Malignant melanoma. Obsolete. ΘΚΠ the world > health and disease > ill health > a disease > diseases of tissue > [noun] > cancer > types of soft cancer1804 soot-wart?1810 melanosis1826 mastoid cancer1846 skin cancer1847 cancroid1854 epithelioma1872 soot-cancer1878 scirrhus1881 chimney-sweep's cancer1888 peau d'orange1896 pigskin1898 medullary carcinoma1926 1826 Lancet 1 Apr. 19/2 The tumour presented all the characters of the cancerous melanosis. 1834 J. Forbes tr. R. T. H. Laennec Treat. Dis. Chest (ed. 4) 355 Melanosis is one of the rarest species of cancer. 1877 F. T. Roberts Handbk. Med. (ed. 3) I. 277 Melanosis and colloid are generally regarded as forms of cancer . 3. Brown or black discoloration of the mucous membrane of a part of the intestinal tract, esp. the colon, often associated with excessive consumption of anthraquinone laxatives. Chiefly in melanosis coli. ΚΠ 1931 Jrnl. Pathol. & Bacteriol. 34 61 At that time [sc. 1847] Virchow did not coin a special name for the condition but in 1858 he provided a specimen, now in the museum of the Pathological Institute at Berlin, labelled in his own hand-writing ‘melanosis coli’. 1931 Jrnl. Pathol. & Bacteriol. 34 62 The first detailed account of the morbid anatomy of melanosis coli was given by Pick in 1911... Pick adopted the term melanosis coli without being aware of its previous use by Virchow. 1982 Jrnl. Submicrosc. Cytol. 14 389 The pigment in melanosis duodeni resides in the lysosomes of macrophages in the lamina propria. 1992 Carcinogenesis 13 2217 Morphological observation of the intestines also revealed melanosis, crypt abscesses and erosion, becoming more pronounced with length of exposure to the anthraquinone. This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022). < n.1821
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