malonicadj.
/məˈlɒnɪk/, U.S. /məˈloʊnɪk/, /məˈlɑnɪk/ Chemistry.
1. malonic acid n. a crystalline acid, CH2(COOH)2, obtainable by oxidation of malic acid; propanedioic acid.
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the world > matter > chemistry > organic chemistry > organic acids > [noun] > carboxylic acids > miscellaneous others
urobenzoic acid1836
adipic acid1838
azelaic acid1838
isethionic acid1838
rutinic acid1845
rutic acid1848
glyoxylic acid1856
malonic acid1859
piperic acid1863
butalanine1865
methacrylic acid1865
barbituric acid1866
pichuric acid1866
carboxylic acid1868
gluconic acid1871
xylic acid1872
xylidic acid1872
aconic acid1873
formobenzoic1873
nicotinic acid1873
hydracrylic acid1877
undecylenic acid1879
isonicotinic acid1883
isatoic acid1885
linolenic acid1887
hendecenoic acid1889
heptenoic acid1889
mannonic acid1890
phenolcarboxylic acid1893
naphthenic acid1894
aldonic acid1904
naphthaleneacetic acid1917
heptanoic acid1928
hexuronic acid1928
pantothenic acid1933
neuraminic acid1942
pantoic acid1945
penicillanic acid1953
mevalonic acid1957
retinoic acid1960
isobutyric acid-
1859 H. Watts tr. L. Gmelin Hand-bk. Chem. XIII. 560 Malonic acid gives off carbonic acid at 150°.
1888 I. Remsen Introd. Study Compounds of Carbon 204 Treated with an alkali, barbituric acid breaks up into malonic acid and urea.
1934 C. C. Steele Introd. Plant Biochem. xii. 124 Glutaric acid, CH·(CH2·(CH2COOH)2, and adipic acid, (CH2·CH2·COOH)2, have been isolated together with malonic acid from the Sugar Beet.
1968 J. H. Burn Lect. Notes Pharmacol. (ed. 9) 52 Barbituric acid is formed by the condensation of malonic acid with urea.
1991 Jrnl. Medicinal Chem. 34 3373/2 The scheme was designed to avoid the use of the malonic acid derivative HOOCCH[(CH2)4NHBoc]COOEt, which can be prepared only in very low amounts.
2. malonic ester n. the diethyl ester, CH2(COOC2H5)2, of malonic acid, which is a liquid widely used in synthesis, as of carboxylic acids RR′C(COOH)2 or RR′CHCOOH by alkylation with alkyl halides ( malonic ester synthesis).
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the world > matter > chemistry > organic chemistry > esters > [noun] > named
oxalic ether1788
margarate1819
acrylate1843
urethane1856
tropeine1880
malonic ester1881
heavy oil of wine1882
phosphatide1884
ethanoate1892
imino-ester1897
acetylcholine1906
phaeophytin1907
phytic acid1908
propiolactone1917
silicon ester1923
methyl methacrylate1933
Tylose1934
testosterone propionate1937
filicin1941
trichothecin1948
siphonein1949
acetyl coenzyme A1950
acetyl CoA1951
1881 Chem. News 28 Jan. 47/1 (heading) Syntheses by means of malonic ester.
1906 G. M'Gowan & J. J. Sudborough Bernthsen's Text-bk. Org. Chem. x. 238 This so-called ‘malonic ester’ synthesis is an important method for the preparation of higher dibasic acids.
1957 R. H. Thomson Naturally Occurring Quinones iii. 147 This..is the basis of the Craven test in which quinones having an unsubstituted position develop a blue colour when treated with alcoholic ammoniacal malonic ester.
1971 N. L. Allinger et al. Org. Chem. xxiv. 665 In the malonic ester synthesis, diethyl malonate is converted by sodium ethoxide into its sodium salt, which is then allowed to react with an alkyl halide.
1989 Encycl. Brit. VII. 742/1 Diethyl malonate, CH2(CO2C2H5)2, also called malonic ester, is prepared by the reaction of ethyl alcohol with cyanoacetic acid.
This entry has been updated (OED Third Edition, June 2000; most recently modified version published online March 2022).
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adj.1859