Malloryn.

Brit.

/ˈmaləri/, U.S.

/ˈmæləri/

Origin: From a proper name. Etymon: proper name Mallory.

Etymology: < the name of Frank B. Mallory (1862–1941), U.S. pathologist.A number of the techniques, including the two specified in senses 1a, 1b, were originally described in Jrnl. Exper. Med. between 1897 and 1900.

Pathology.

1. attributive and in the genitive. Designating various staining techniques devised by Mallory.

a. Used with reference to a staining technique using haematoxylin and phosphotungstic acid to demonstrate connective tissue elements and cytological detail; esp. in Mallory's phosphotungstic acid haematoxylin, Mallory's phosphotungstic acid haematoxylin stain.

ΚΠ

1900 A. B. Lee Microtomist's Vade-Mecum (ed. 5) xiii. 192 Mallory's Phosphotungstic Acid Hæmatoxylin.

1918 F. B. Mallory & J. H. Wright Pathol. Technique (ed. 7) 71 Mallory's Phosphotungstic Acid Hematoxylin.

1936 J. H. Biggart Pathol. Nervous Syst. ii. 22 (caption) Swollen glial cells... Mallory's phosphotungstic acid hæmatoxylin.

1968 Brain 91 409 The rodlets and granules were best seen with Mallory's phosphotungstic acid, by which they were stained dark blue.

1986 Canad. Jrnl. Ophthalmol. 21 178 The granules stain blue with Mallory's phosphotungstic acid hematoxylin and can be identified as mitochondria by electron microscopy.

1994 Human Pathol. 25 1283 Cartilage associated HGs [sc. hyaline globules]..demonstrated autofluorescence, and variably stained with Mallory's phosphotungstic acid-hematoxylin stain (PTAH).

b. Used with reference to a staining technique using acid fuchsin, aniline blue, orange G, and phosphotungstic (originally phosphomolybdic) acid to produce differential staining of collagen and ground substance (blue), nuclei, fibrin and neuroglia (red), elastin (yellow or pink), etc.; now esp. in Mallory's trichrome stain, Mallory's triple stain.

ΚΠ

1905 I. W. Hall & G. Herxheimer Methods in Morbid Histol. xi. 83 Mallory's Aniline Blue Method.

1910 E. A. S. Schaefer Essent. Histol. (ed. 8) App. 557 (heading) Mallory's stain for connective tissue.

1928 J. B. Gatenby & E. V. Cowdry Lee's Microtomist's Vade-mecum (ed. 9) 435 Mallory's triple stain is useful for differentiating tissues containing parasites.

1939 T. L. Green Pract. Animal Biol. iii. 242 The section should be stained with Mallory's Triple Stain.

1968 B. H. McConnaughey in M. Florkin & B. T. Scheer Chem. Zool. II. iii. viii. 567 During early development of the infusoriform the material of which these refractile bodies are composed stains blue with Mallory triple stain for connective tissue.

1985 C. R. Leeson et al. Textbk. Histol. (ed. 5) 11/2 Trichrome methods, such as Mallory's connective tissue stain and the Mallory-Azan method, possess the advantage that they differentiate between cytoplasmic structures and intercellular materials.

1991 Circulation 83 237 The area at risk was defined in vivo with Monastral blue, and infarct size was measured histologically with Mallory's trichrome stain.

a. Mallory body n. [described by Mallory 1911, in Bull. Johns Hopkins Hosp. 22 73] an irregularly shaped, eosinophilic cytoplasmic inclusion seen in hepatocytes in alcoholic and various other liver diseases.

ΚΠ

1947 Arch. Internal Med. 80 398 The presence of Mallory bodies is the most important and constant single feature.

1976 Pathol. Ann. 11 71 The Mallory body is distinguished from viral inclusions by its angulated dendritic or ameboid outline, its distinctive reddish-purple staining, and its hyalinelike refractile density.

1991 Brit. Med. Jrnl. 16 Mar. 662/2 Dr. A. Ireland and colleagues found only reversible histological changes (steatosis and Mallory bodies), although fibrosis or cirrhosis was a common finding in patients with additional abnormalities of serum liver biochemistry.

b. Mallory's hyaline n. (also Mallory's alcoholic hyaline) the eosinophilic material of which Mallory bodies are composed, probably consisting of abnormal cytoskeletal elements; Mallory bodies collectively.

ΚΠ

1968 New Eng. Jrnl. Med. 18 Apr. 872/1 In several specimens from Groups 1 and 2, occasional focal necrosis was observed after alcohol administration. Mallory's ‘alcoholic hyaline’ or fibrosis were never found.

1984 J. R. Tighe & D. R. Davies Pathol. (ed. 4) xvii. 162 Some drinkers develop a hepatitis which is characterized by..a curious degenerative change (known as Mallory's hyaline) in the cytoplasm of some parenchymal cells.

1995 Ann. Trop. Paediatr. 15 237 Histologically, fatty change was absent from all the biopsies but Mallory's hyaline, pericellular fibrosis and ballooning of hepatocytes were present in some.

This is a new entry (OED Third Edition, June 2000; most recently modified version published online March 2022).

单词	mallory
释义	Malloryn. Brit. /ˈmaləri/, U.S. /ˈmæləri/ Origin: From a proper name. Etymon: proper name Mallory. Etymology: < the name of Frank B. Mallory (1862–1941), U.S. pathologist.A number of the techniques, including the two specified in senses 1a, 1b, were originally described in Jrnl. Exper. Med. between 1897 and 1900. Pathology. 1. attributive and in the genitive. Designating various staining techniques devised by Mallory. a. Used with reference to a staining technique using haematoxylin and phosphotungstic acid to demonstrate connective tissue elements and cytological detail; esp. in Mallory's phosphotungstic acid haematoxylin, Mallory's phosphotungstic acid haematoxylin stain. ΚΠ 1900 A. B. Lee Microtomist's Vade-Mecum (ed. 5) xiii. 192 Mallory's Phosphotungstic Acid Hæmatoxylin. 1918 F. B. Mallory & J. H. Wright Pathol. Technique (ed. 7) 71 Mallory's Phosphotungstic Acid Hematoxylin. 1936 J. H. Biggart Pathol. Nervous Syst. ii. 22 (caption) Swollen glial cells... Mallory's phosphotungstic acid hæmatoxylin. 1968 Brain 91 409 The rodlets and granules were best seen with Mallory's phosphotungstic acid, by which they were stained dark blue. 1986 Canad. Jrnl. Ophthalmol. 21 178 The granules stain blue with Mallory's phosphotungstic acid hematoxylin and can be identified as mitochondria by electron microscopy. 1994 Human Pathol. 25 1283 Cartilage associated HGs [sc. hyaline globules]..demonstrated autofluorescence, and variably stained with Mallory's phosphotungstic acid-hematoxylin stain (PTAH). b. Used with reference to a staining technique using acid fuchsin, aniline blue, orange G, and phosphotungstic (originally phosphomolybdic) acid to produce differential staining of collagen and ground substance (blue), nuclei, fibrin and neuroglia (red), elastin (yellow or pink), etc.; now esp. in Mallory's trichrome stain, Mallory's triple stain. ΚΠ 1905 I. W. Hall & G. Herxheimer Methods in Morbid Histol. xi. 83 Mallory's Aniline Blue Method. 1910 E. A. S. Schaefer Essent. Histol. (ed. 8) App. 557 (heading) Mallory's stain for connective tissue. 1928 J. B. Gatenby & E. V. Cowdry Lee's Microtomist's Vade-mecum (ed. 9) 435 Mallory's triple stain is useful for differentiating tissues containing parasites. 1939 T. L. Green Pract. Animal Biol. iii. 242 The section should be stained with Mallory's Triple Stain. 1968 B. H. McConnaughey in M. Florkin & B. T. Scheer Chem. Zool. II. iii. viii. 567 During early development of the infusoriform the material of which these refractile bodies are composed stains blue with Mallory triple stain for connective tissue. 1985 C. R. Leeson et al. Textbk. Histol. (ed. 5) 11/2 Trichrome methods, such as Mallory's connective tissue stain and the Mallory-Azan method, possess the advantage that they differentiate between cytoplasmic structures and intercellular materials. 1991 Circulation 83 237 The area at risk was defined in vivo with Monastral blue, and infarct size was measured histologically with Mallory's trichrome stain. 2. a. Mallory body n. [described by Mallory 1911, in Bull. Johns Hopkins Hosp. 22 73] an irregularly shaped, eosinophilic cytoplasmic inclusion seen in hepatocytes in alcoholic and various other liver diseases. ΚΠ 1947 Arch. Internal Med. 80 398 The presence of Mallory bodies is the most important and constant single feature. 1976 Pathol. Ann. 11 71 The Mallory body is distinguished from viral inclusions by its angulated dendritic or ameboid outline, its distinctive reddish-purple staining, and its hyalinelike refractile density. 1991 Brit. Med. Jrnl. 16 Mar. 662/2 Dr. A. Ireland and colleagues found only reversible histological changes (steatosis and Mallory bodies), although fibrosis or cirrhosis was a common finding in patients with additional abnormalities of serum liver biochemistry. b. Mallory's hyaline n. (also Mallory's alcoholic hyaline) the eosinophilic material of which Mallory bodies are composed, probably consisting of abnormal cytoskeletal elements; Mallory bodies collectively. ΚΠ 1968 New Eng. Jrnl. Med. 18 Apr. 872/1 In several specimens from Groups 1 and 2, occasional focal necrosis was observed after alcohol administration. Mallory's ‘alcoholic hyaline’ or fibrosis were never found. 1984 J. R. Tighe & D. R. Davies Pathol. (ed. 4) xvii. 162 Some drinkers develop a hepatitis which is characterized by..a curious degenerative change (known as Mallory's hyaline) in the cytoplasm of some parenchymal cells. 1995 Ann. Trop. Paediatr. 15 237 Histologically, fatty change was absent from all the biopsies but Mallory's hyaline, pericellular fibrosis and ballooning of hepatocytes were present in some. This is a new entry (OED Third Edition, June 2000; most recently modified version published online March 2022). < n.1900
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