malignancyn.

Brit.

/məˈlɪɡnənsi/, U.S.

/məˈlɪɡnənsi/

Forms: 1600s malignancie, 1600s– malignancy.

Origin: Either (i) formed within English, by derivation. Or (ii) a borrowing from Latin. Etymons: malignant adj., -ancy suffix; Latin malignantia.

Etymology: Either < malignant adj. (see -ancy suffix), or directly < post-classical Latin malignantia (late 12th cent. in a British source) < malignant- (see malignant adj.) + -ia -y suffix³. Compare slightly earlier malignance n.

1. Something that is malignant; a malignant quality.

ΘΚΠ

the world > action or operation > behaviour > bad behaviour > unkindness > ill will, malevolence > [noun] > instance of

disfavour1556

malignancy1609

1609 C. Tourneur Funerall Poeme sig. C2 That had the strength of patience to dispise The bitter censures of malignancies, In managements so subiect to construction.

1682 N. Grew Idea Philos. Hist. Plants 5 in Anat. Plants What may best correct their Malignancies, or inforce their Virtues.

1843 Southern Q. Rev. July 198 First physicians were a species of conjurors, or wizards... Incantations, sorceries and mummeries of divers kinds, were the means which they employed to counteract the causes of imaginary malignancy.

1869 H. Bushnell Women's Suffrage vii. 141 They let in also little malignancies that are poisonous.

1899 Daily News 29 May 8/5 The merits of whose members compensate for the malignancies of their [golf] course.

1986 B. Gilroy Frangipani House viii. 36 Mama King smouldered. A malignancy came over her wrinkled face.

†2. Malign or baleful character; unpropitiousness; great injuriousness. Obsolete.

ΘΚΠ

the world > the universe > heavenly body > as influence on mankind > [noun] > nature of > malign

malignancya1616

malefice1652

the world > health and disease > ill health > insalubrity > [noun]

infirmity1481

unwholesomenessa1513

contagiousness1530

evilness1563

malignity1585

unhealthfulness1598

untemperaturea1604

unhealthsomeness1613

healthlessness1655

unsoundness1660

insalubrity1663

unhealthiness1666

unsalubrity1694

malignancy1732

pestilentiousness1748

mal-influence1792

insanitariness1881

insanitation1884

a1616 W. Shakespeare Twelfth Night (1623) ii. i. 4 My starres shine darkely ouer me; the malignancie of my fate, might perhaps distemper yours.

1656 T. Stanley Hist. Philos. II. v. 101 Jupiter [is placed] next Saturn, to abate his malignancy.

1732 True & Faithful Narr. in J. Swift Misc. III. ii. 269 There might be a Pestilential Malignancy in the Air, occasion'd by the Comet.

3. Malignant or intensely malevolent disposition; envenomed hostility; desire to inflict injury or suffering.

ΘΚΠ

the mind > goodness and badness > harmfulness > ill-will > [noun]

evil willc897

leth971

loathc1175

atterness?c1225

ill1303

maltalentc1330

ill-willingnessa1340

talenta1380

malignityc1390

ill willa1400

fellnessc1410

malevolencec1454

malignation?c1500

hatefulness1548

malignance1605

malevolency1635

malignancy1640

reptilism1821

fiendism1852

unbenignity1867

the world > action or operation > behaviour > bad behaviour > unkindness > ill will, malevolence > [noun]

evil willc897

leth971

loathc1175

atterness?c1225

ill1303

maltalentc1330

ill-willingnessa1340

talenta1380

malignityc1390

ill willa1400

with hard (also sorry) gracec1405

malevolencec1454

malignation?c1500

malignitiesa1529

hatefulness1548

malignance1605

fiendishness1613

malevolency1635

malignancy1640

fellness1678

malevolentness1727

malignantness1727

reptilism1821

unbenignity1867

1640 J. Howell Δενδρολογια 109 His eldest Graff succeeded him a while in Royall favour; but he quickly fell, by the malignancie of great ones.

1683 J. Dryden Life Plutarch 43 in J. Dryden et al. tr. Plutarch Lives I The meer malignancy of a Spirit delighted naturally in mischief.

1706 tr. J. B. Morvan de Bellegarde Refl. upon Ridicule 390 Penetration gives her more Artifice and Malignancy.

1782 E. Blower George Bateman III. 118 The malignancy of disappointed playwrights.

1856 J. A. Froude Hist. Eng. (1858) I. i. 17 A war unequalled in history for its fierce and determined malignancy.

1897 M. Kingsley Trav. W. Afr. 505 If a man were..shot with an arrow, the cause of death is clearly the malignancy of the person using these weapons.

1927 A. Conan Doyle in Strand Mag. Feb. 114/1 One could conceive those small, vicious eyes darting pure malignancy as they looked forth upon the world.

1990 D. McFarland Music Room 91 I was getting strong hits of my own malignancy and sloth.

†4. Disaffection to constituted authority; spec. (originally depreciative) sympathy with the Royalist cause during the English Civil War. Cf. malignant n. Obsolete.

ΘΚΠ

society > authority > lack of subjection > rebelliousness > political disaffection > [noun]

disaffection1607

malignancy1644

antarchy1656

1644 (title) A medicine for malignancy: or Parliament pill serving to purge out the malignant humours of men disaffected to the Republic.

1645 in J. B. Greenshields Ann. Parish Lesmahagow (1864) 153 The Lady Marquesse of Douglasse,..being gravely examined anent her malignancie and obstinate continewance in the profession of poperie.

1647 T. May Hist. Parl. ii. i. 3 The malignancy, which at that time began to appear in people.

1649 J. Milton Εικονοκλαστης ix. 84 Many of the Lords and some few of the Commons, either intic'd away by the King, or overaw'd by the sence of thir own Malignancy not prevailing, deserted the Parlament.

1660 R. Burney Κέρδιστον Δῶρον Ep. Ded. sig. A2 ^v Each holy Text that mentioned a King, was then a note of Malignancy.

5. Medicine.

a. The property of being malignant (see malignant adj. 3a); the degree to which a neoplasm or (formerly) other type of disease is malignant. Now also: malignant neoplastic disease.

ΘΚΠ

the world > health and disease > ill health > a disease > characteristics > [noun] > degree of intensity > violence or severity

malicea1382

vehemency?1541

malignity1543

acutenessa1644

virulency1651

malignancy1693

virulence1748

severity1808

acuity1839

fulminancy1887

1693 Philos. Trans. (Royal Soc.) 17 726 The Fever inclining to Malignancy.

a1706 J. Evelyn Life Mrs. Godolphin (1939) 77 There appearing a kind of Eresypelas..the Malignancy grew desperate.

1720 D. Defoe Mem. Cavalier 28 A slow..Fever..turned to a burning Malignancy.

1826 S. Cooper First Lines Pract. Surg. (ed. 5) i. xxvi. 202 It cannot be cured without an operation; but it is quite free from malignancy.

1898 Arch. Surg. 9 295 The tumour..was..so suggestive of malignancy that amputation was contemplated.

1929 Radiology 13 316/2 Squamous carcinoma, malignancy of varying grades.

1952 G. H. Bourne Cytol. & Cell Physiol. (ed. 2) ix. 406 Apart from their capacity to induce malignancy, these agents have one cytological action in common.

1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) vi. 695 The most important characteristic of malignancy is the ability to metastasise.

1998 New Scientist 7 Feb. 78/2 (advt.) A research programme on tissue factor, thrombin generation and human pancreatic malignancy.

b. A malignant neoplasm.

ΘΚΠ

the world > health and disease > ill health > a disease > growth or excrescence > [noun] > tumour > malignant tumours

cancer1527

carcinoma1583

crab1614

scirrhus1759

sarcoma1804

malignant melanoma1838

melanocarcinoma1857

adenosarcoma1871

adenocarcinoma1872

angiosarcoma1873

lymphosarcoma1874

mycosis fungoides1874

melanosarcoma1875

osteosarcoma1876

chondrosarcoma1883

psammosarcoma1886

trophoblast1889

liposarcoma1893

multiple myeloma1897

sarcoid1899

leiomyosarcoma1914

spongioblastoma1918

osteogenic sarcoma1923

sympathicoblastoma1927

reticulosarcoma1928

carcinoma in situ1932

malignancy1934

teratocarcinoma1946

sympathoblastoma1960

sympathogonioma1966

sympathicogonioma1974

1934 Webster's New Internat. Dict. Eng. Lang. Malignancy,..a malignant tumor; as, a malignancy of the breast.

1935 C. J. Imperatori & H. J. Burman Dis. Nose & Throat xxx. 352 Operable malignancies are those which are limited to the soft palate, or uvula.

1974 Anderson (S. Carolina) Independent 24 Apr. 4 a/3 She told me the doctor had just told Mr. Coffee he had a malignancy and she wanted me to know.

1988 P. Gay Freud xii. 634 Freud stopped work..in early September, when there were alarming signs that his malignancy was active once again.

1993 New Scientist 4 Dec. 23/2 The bleeding is not a problem as it is not an indication of a malignancy.

This entry has been updated (OED Third Edition, June 2000; most recently modified version published online March 2022).

单词	malignancy
释义	malignancyn. Brit. /məˈlɪɡnənsi/, U.S. /məˈlɪɡnənsi/ Forms: 1600s malignancie, 1600s– malignancy. Origin: Either (i) formed within English, by derivation. Or (ii) a borrowing from Latin. Etymons: malignant adj., -ancy suffix; Latin malignantia. Etymology: Either < malignant adj. (see -ancy suffix), or directly < post-classical Latin malignantia (late 12th cent. in a British source) < malignant- (see malignant adj.) + -ia -y suffix³. Compare slightly earlier malignance n. 1. Something that is malignant; a malignant quality. ΘΚΠ the world > action or operation > behaviour > bad behaviour > unkindness > ill will, malevolence > [noun] > instance of disfavour1556 malignancy1609 1609 C. Tourneur Funerall Poeme sig. C2 That had the strength of patience to dispise The bitter censures of malignancies, In managements so subiect to construction. 1682 N. Grew Idea Philos. Hist. Plants 5 in Anat. Plants What may best correct their Malignancies, or inforce their Virtues. 1843 Southern Q. Rev. July 198 First physicians were a species of conjurors, or wizards... Incantations, sorceries and mummeries of divers kinds, were the means which they employed to counteract the causes of imaginary malignancy. 1869 H. Bushnell Women's Suffrage vii. 141 They let in also little malignancies that are poisonous. 1899 Daily News 29 May 8/5 The merits of whose members compensate for the malignancies of their [golf] course. 1986 B. Gilroy Frangipani House viii. 36 Mama King smouldered. A malignancy came over her wrinkled face. †2. Malign or baleful character; unpropitiousness; great injuriousness. Obsolete. ΘΚΠ the world > the universe > heavenly body > as influence on mankind > [noun] > nature of > malign malignancya1616 malefice1652 the world > health and disease > ill health > insalubrity > [noun] infirmity1481 unwholesomenessa1513 contagiousness1530 evilness1563 malignity1585 unhealthfulness1598 untemperaturea1604 unhealthsomeness1613 healthlessness1655 unsoundness1660 insalubrity1663 unhealthiness1666 unsalubrity1694 malignancy1732 pestilentiousness1748 mal-influence1792 insanitariness1881 insanitation1884 a1616 W. Shakespeare Twelfth Night (1623) ii. i. 4 My starres shine darkely ouer me; the malignancie of my fate, might perhaps distemper yours. View more context for this quotation 1656 T. Stanley Hist. Philos. II. v. 101 Jupiter [is placed] next Saturn, to abate his malignancy. 1732 True & Faithful Narr. in J. Swift Misc. III. ii. 269 There might be a Pestilential Malignancy in the Air, occasion'd by the Comet. 3. Malignant or intensely malevolent disposition; envenomed hostility; desire to inflict injury or suffering. ΘΚΠ the mind > goodness and badness > harmfulness > ill-will > [noun] evil willc897 leth971 loathc1175 atterness?c1225 ill1303 maltalentc1330 ill-willingnessa1340 talenta1380 malignityc1390 ill willa1400 fellnessc1410 malevolencec1454 malignation?c1500 hatefulness1548 malignance1605 malevolency1635 malignancy1640 reptilism1821 fiendism1852 unbenignity1867 the world > action or operation > behaviour > bad behaviour > unkindness > ill will, malevolence > [noun] evil willc897 leth971 loathc1175 atterness?c1225 ill1303 maltalentc1330 ill-willingnessa1340 talenta1380 malignityc1390 ill willa1400 with hard (also sorry) gracec1405 malevolencec1454 malignation?c1500 malignitiesa1529 hatefulness1548 malignance1605 fiendishness1613 malevolency1635 malignancy1640 fellness1678 malevolentness1727 malignantness1727 reptilism1821 unbenignity1867 1640 J. Howell Δενδρολογια 109 His eldest Graff succeeded him a while in Royall favour; but he quickly fell, by the malignancie of great ones. 1683 J. Dryden Life Plutarch 43 in J. Dryden et al. tr. Plutarch Lives I The meer malignancy of a Spirit delighted naturally in mischief. 1706 tr. J. B. Morvan de Bellegarde Refl. upon Ridicule 390 Penetration gives her more Artifice and Malignancy. 1782 E. Blower George Bateman III. 118 The malignancy of disappointed playwrights. 1856 J. A. Froude Hist. Eng. (1858) I. i. 17 A war unequalled in history for its fierce and determined malignancy. 1897 M. Kingsley Trav. W. Afr. 505 If a man were..shot with an arrow, the cause of death is clearly the malignancy of the person using these weapons. 1927 A. Conan Doyle in Strand Mag. Feb. 114/1 One could conceive those small, vicious eyes darting pure malignancy as they looked forth upon the world. 1990 D. McFarland Music Room 91 I was getting strong hits of my own malignancy and sloth. †4. Disaffection to constituted authority; spec. (originally depreciative) sympathy with the Royalist cause during the English Civil War. Cf. malignant n. Obsolete. ΘΚΠ society > authority > lack of subjection > rebelliousness > political disaffection > [noun] disaffection1607 malignancy1644 antarchy1656 1644 (title) A medicine for malignancy: or Parliament pill serving to purge out the malignant humours of men disaffected to the Republic. 1645 in J. B. Greenshields Ann. Parish Lesmahagow (1864) 153 The Lady Marquesse of Douglasse,..being gravely examined anent her malignancie and obstinate continewance in the profession of poperie. 1647 T. May Hist. Parl. ii. i. 3 The malignancy, which at that time began to appear in people. 1649 J. Milton Εικονοκλαστης ix. 84 Many of the Lords and some few of the Commons, either intic'd away by the King, or overaw'd by the sence of thir own Malignancy not prevailing, deserted the Parlament. 1660 R. Burney Κέρδιστον Δῶρον Ep. Ded. sig. A2 ^v Each holy Text that mentioned a King, was then a note of Malignancy. 5. Medicine. a. The property of being malignant (see malignant adj. 3a); the degree to which a neoplasm or (formerly) other type of disease is malignant. Now also: malignant neoplastic disease. ΘΚΠ the world > health and disease > ill health > a disease > characteristics > [noun] > degree of intensity > violence or severity malicea1382 vehemency?1541 malignity1543 acutenessa1644 virulency1651 malignancy1693 virulence1748 severity1808 acuity1839 fulminancy1887 1693 Philos. Trans. (Royal Soc.) 17 726 The Fever inclining to Malignancy. a1706 J. Evelyn Life Mrs. Godolphin (1939) 77 There appearing a kind of Eresypelas..the Malignancy grew desperate. 1720 D. Defoe Mem. Cavalier 28 A slow..Fever..turned to a burning Malignancy. 1826 S. Cooper First Lines Pract. Surg. (ed. 5) i. xxvi. 202 It cannot be cured without an operation; but it is quite free from malignancy. 1898 Arch. Surg. 9 295 The tumour..was..so suggestive of malignancy that amputation was contemplated. 1929 Radiology 13 316/2 Squamous carcinoma, malignancy of varying grades. 1952 G. H. Bourne Cytol. & Cell Physiol. (ed. 2) ix. 406 Apart from their capacity to induce malignancy, these agents have one cytological action in common. 1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) vi. 695 The most important characteristic of malignancy is the ability to metastasise. 1998 New Scientist 7 Feb. 78/2 (advt.) A research programme on tissue factor, thrombin generation and human pancreatic malignancy. b. A malignant neoplasm. ΘΚΠ the world > health and disease > ill health > a disease > growth or excrescence > [noun] > tumour > malignant tumours cancer1527 carcinoma1583 crab1614 scirrhus1759 sarcoma1804 malignant melanoma1838 melanocarcinoma1857 adenosarcoma1871 adenocarcinoma1872 angiosarcoma1873 lymphosarcoma1874 mycosis fungoides1874 melanosarcoma1875 osteosarcoma1876 chondrosarcoma1883 psammosarcoma1886 trophoblast1889 liposarcoma1893 multiple myeloma1897 sarcoid1899 leiomyosarcoma1914 spongioblastoma1918 osteogenic sarcoma1923 sympathicoblastoma1927 reticulosarcoma1928 carcinoma in situ1932 malignancy1934 teratocarcinoma1946 sympathoblastoma1960 sympathogonioma1966 sympathicogonioma1974 1934 Webster's New Internat. Dict. Eng. Lang. Malignancy,..a malignant tumor; as, a malignancy of the breast. 1935 C. J. Imperatori & H. J. Burman Dis. Nose & Throat xxx. 352 Operable malignancies are those which are limited to the soft palate, or uvula. 1974 Anderson (S. Carolina) Independent 24 Apr. 4 a/3 She told me the doctor had just told Mr. Coffee he had a malignancy and she wanted me to know. 1988 P. Gay Freud xii. 634 Freud stopped work..in early September, when there were alarming signs that his malignancy was active once again. 1993 New Scientist 4 Dec. 23/2 The bleeding is not a problem as it is not an indication of a malignancy. This entry has been updated (OED Third Edition, June 2000; most recently modified version published online March 2022). < n.1609
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