Mapharsenn.

Brit.

/maˈfɑːsən/, U.S.

/ˌmæˈfɑrsən/

Forms: also with lower-case initial.

Origin: Formed within English, by derivation. Etymons: meta- prefix, amino- comb. form, para- prefix¹, hydroxyl n., arsenic n.

Etymology: < m- (in meta- prefix) + a- (in amino- comb. form) + p- (in para- prefix¹) + h- (in hydroxyl n.) + arsen- (in arsenic n.): see quot. 1932.

Pharmacology (chiefly U.S.). Now historical.

An organic arsenical drug formerly given intravenously in the treatment of syphilis; the hydrochloride of 3-amino-4-hydroxyphenyloxoarsine, (HO)(H₂N)C₆H₃·AsO. Cf. Mapharside n.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for venereal disease or syphilis > for syphilis and yaws

Salvarsan1910

arsphenamine1917

Mapharsen1932

Mapharside1936

1932 A. L. Tatum & G. A. Cooper in Science 20 May 541/2 We have been designating this drug as ‘158’, or more or less tentatively by the name Mapharsen from (m)eta-(a)mino-(p)ara-(h)ydroxy (ars)ine oxide.

1934 A. L. Tatum & G. A. Cooper in Jrnl. Pharmacol. & Exper. Therapeutics 50 198 The drug, meta-amino para-hydroxyl phenyl arsine oxide, we designate as Drug No. 158 or, by name, Mapharsen.

1946 Jrnl. Venereal Dis. Information 27 9/1 Penicillin and mapharsen are synergistic in the treatment of experimental syphilis.

1949 H. Wilcox Six Moons in Sulawesi xiii. 297 The contrast between the ugly sore swellings of those not yet treated and the state of others who had received half their series of injections (it was mapharsen, I think) was gratifying.

1985 Jrnl. Hist. Med. 40 187 Mapharsen..provided physicians with a comparatively safe and effective treatment for syphilis for several years until it was replaced by penicillin.

This entry has been updated (OED Third Edition, September 2000; most recently modified version published online March 2022).

单词	mapharsen
释义	Mapharsenn. Brit. /maˈfɑːsən/, U.S. /ˌmæˈfɑrsən/ Forms: also with lower-case initial. Origin: Formed within English, by derivation. Etymons: meta- prefix, amino- comb. form, para- prefix¹, hydroxyl n., arsenic n. Etymology: < m- (in meta- prefix) + a- (in amino- comb. form) + p- (in para- prefix¹) + h- (in hydroxyl n.) + arsen- (in arsenic n.): see quot. 1932. Pharmacology (chiefly U.S.). Now historical. An organic arsenical drug formerly given intravenously in the treatment of syphilis; the hydrochloride of 3-amino-4-hydroxyphenyloxoarsine, (HO)(H₂N)C₆H₃·AsO. Cf. Mapharside n. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for venereal disease or syphilis > for syphilis and yaws Salvarsan1910 arsphenamine1917 Mapharsen1932 Mapharside1936 1932 A. L. Tatum & G. A. Cooper in Science 20 May 541/2 We have been designating this drug as ‘158’, or more or less tentatively by the name Mapharsen from (m)eta-(a)mino-(p)ara-(h)ydroxy (ars)ine oxide. 1934 A. L. Tatum & G. A. Cooper in Jrnl. Pharmacol. & Exper. Therapeutics 50 198 The drug, meta-amino para-hydroxyl phenyl arsine oxide, we designate as Drug No. 158 or, by name, Mapharsen. 1946 Jrnl. Venereal Dis. Information 27 9/1 Penicillin and mapharsen are synergistic in the treatment of experimental syphilis. 1949 H. Wilcox Six Moons in Sulawesi xiii. 297 The contrast between the ugly sore swellings of those not yet treated and the state of others who had received half their series of injections (it was mapharsen, I think) was gratifying. 1985 Jrnl. Hist. Med. 40 187 Mapharsen..provided physicians with a comparatively safe and effective treatment for syphilis for several years until it was replaced by penicillin. This entry has been updated (OED Third Edition, September 2000; most recently modified version published online March 2022). < n.1932
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