英语词汇“lock and key”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典

c. In collocation with key, chiefly as lock and key.

(a) Also (more rarely) as key and lock. Any device for fastening or securing something, together with the means to open or close it. Also figurative and in figurative contexts. Occasionally attributive. Cf. under lock and key at Phrases 1.In quot. 1899: (perhaps) inscrutable.

ΘΚΠ

society > occupation and work > equipment > building and constructing equipment > fastenings > [noun] > lock > and key

key lokeOE

key and lockc1275

lock and key1413

the world > relative properties > relationship > correlation > [phrase] > lock and key

lock and key1413

OE tr. Gospel of Nicodemus (Cambr.) xii. §2. 171 Hig uninseglodon þæt loc and þa cægan and þa duru geopenigende [L. aperientes clauem et signa hostii].]

c1275 (?c1250) Owl & Nightingale (Calig.) (1935) 1557 He hire bi luþ mid keie & loke.

1413 T. Hoccleve Balade Richard II l. 24 in Minor Poems (1970) i. 48 He, of thy soules helthe, is lok and keye!

?c1500 Killing of Children (Digby) l. 389 God, that art both lok and keye of all goodnesse.

1522 in S. Tymms Wills & Inventories Bury St. Edmunds (1850) 116 A rownde tabyll of waynskott w^t lok and key.

1635 J. Hayward tr. G. F. Biondi Donzella Desterrada ii. 105 The foremost [room] whereof was assured with a good lock and key.

1663 Inventory in Ars Quatuor Coronatorum (1896) 9 38 The names of the Accepted Masons in a faire enclosed frame with a lock and key.

1726 Whole Art & Myst. of Mod. Gaming 109 They had Drawers, with Lock and Key, made for each of them to put their Sticks into, in the Billiard Room.

1862 G. Borrow Wild Wales (ed. 2) 200 A small leather satchel with a lock and key.

1873 D. M. Ogilvy Poems (ed. 2) 20 With my lock and key I restrain the sea, And I breathe in the boreal blast.

1899 M. Cholmondeley Red Pottage 224 She has a lock-and-key face.

1977 R. Duncan in New Poetry June 9 It is a superstition of our time that this sexuality is all, is lock and key, the body's deepest sleep and waking.

1994 P. James & N. Thorpe Anc. Inventions x. 468 The ‘Homeric lock’ stands between the simple bolt and proper key-and-lock mechanisms.

2011 R. Doetsch Half-past Dawn 150 The files were not of a secret nature requiring lock and key.

(b) Biology. The active site of an enzyme, antibody, etc., and the site on a substrate to which it binds, esp. when these are complementary in shape. Chiefly attributive. [After German wie Schloss und Schlüssel like lock and key (E. Fischer 1894, in Berichte der Deutsch. Chem. Ges. 27 2992).]

ΚΠ

1901 C. A. Mitchell tr. C. Oppenheimer Ferments v. 65 Two haptophore groups coinciding with one another (‘lock and key’) and a subsequently active zymophore group.

1924 K. G. Falk Chem. Enzyme Actions (ed. 2) v. 116 E. Fischer's lock-and-key simile for the mutual getting together of substrate and enzyme, each fitting in with the other, gives a mechanical picture of the action.

1969 Times 25 Apr. 13/6 It seems that some of the proteins in the mixture are able to recognize and bind to certain sites on the RNA molecule by a lock-and-key mechanism.

2012 M. Williamson How Proteins Work v. 199 The lock and key model has been replaced by the induced-fit model.

单词	lock and key
释义	> as lemmas lock and key c. In collocation with key, chiefly as lock and key. (a) Also (more rarely) as key and lock. Any device for fastening or securing something, together with the means to open or close it. Also figurative and in figurative contexts. Occasionally attributive. Cf. under lock and key at Phrases 1.In quot. 1899: (perhaps) inscrutable. ΘΚΠ society > occupation and work > equipment > building and constructing equipment > fastenings > [noun] > lock > and key key lokeOE key and lockc1275 lock and key1413 the world > relative properties > relationship > correlation > [phrase] > lock and key lock and key1413 OE tr. Gospel of Nicodemus (Cambr.) xii. §2. 171 Hig uninseglodon þæt loc and þa cægan and þa duru geopenigende [L. aperientes clauem et signa hostii].] c1275 (?c1250) Owl & Nightingale (Calig.) (1935) 1557 He hire bi luþ mid keie & loke. 1413 T. Hoccleve Balade Richard II l. 24 in Minor Poems (1970) i. 48 He, of thy soules helthe, is lok and keye! ?c1500 Killing of Children (Digby) l. 389 God, that art both lok and keye of all goodnesse. 1522 in S. Tymms Wills & Inventories Bury St. Edmunds (1850) 116 A rownde tabyll of waynskott w^t lok and key. 1635 J. Hayward tr. G. F. Biondi Donzella Desterrada ii. 105 The foremost [room] whereof was assured with a good lock and key. 1663 Inventory in Ars Quatuor Coronatorum (1896) 9 38 The names of the Accepted Masons in a faire enclosed frame with a lock and key. 1726 Whole Art & Myst. of Mod. Gaming 109 They had Drawers, with Lock and Key, made for each of them to put their Sticks into, in the Billiard Room. 1862 G. Borrow Wild Wales (ed. 2) 200 A small leather satchel with a lock and key. 1873 D. M. Ogilvy Poems (ed. 2) 20 With my lock and key I restrain the sea, And I breathe in the boreal blast. 1899 M. Cholmondeley Red Pottage 224 She has a lock-and-key face. 1977 R. Duncan in New Poetry June 9 It is a superstition of our time that this sexuality is all, is lock and key, the body's deepest sleep and waking. 1994 P. James & N. Thorpe Anc. Inventions x. 468 The ‘Homeric lock’ stands between the simple bolt and proper key-and-lock mechanisms. 2011 R. Doetsch Half-past Dawn 150 The files were not of a secret nature requiring lock and key. (b) Biology. The active site of an enzyme, antibody, etc., and the site on a substrate to which it binds, esp. when these are complementary in shape. Chiefly attributive. [After German wie Schloss und Schlüssel like lock and key (E. Fischer 1894, in Berichte der Deutsch. Chem. Ges. 27 2992).] ΚΠ 1901 C. A. Mitchell tr. C. Oppenheimer Ferments v. 65 Two haptophore groups coinciding with one another (‘lock and key’) and a subsequently active zymophore group. 1924 K. G. Falk Chem. Enzyme Actions (ed. 2) v. 116 E. Fischer's lock-and-key simile for the mutual getting together of substrate and enzyme, each fitting in with the other, gives a mechanical picture of the action. 1969 Times 25 Apr. 13/6 It seems that some of the proteins in the mixture are able to recognize and bind to certain sites on the RNA molecule by a lock-and-key mechanism. 2012 M. Williamson How Proteins Work v. 199 The lock and key model has been replaced by the induced-fit model. extracted from lockn.² < as lemmas
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> as lemmas