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单词 loading dose
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loading dose
loading dose n. Medicine a large dose of a drug administered at the beginning of a course of treatment in order to achieve a therapeutic concentration in the body quickly.
ΘΚΠ
the world > health and disease > healing > medicines or physic > [noun] > dose of medicine > types of dose
overdose1700
under-dose1822
challenge1935
booster1950
loading dose1961
bolus1967
1961 Lancet 19 Aug. 400/2 Cortisone 250 mg. by intramuscular injection was given as a loading dose.
1976 Lancet 20 Nov. 1143/2 Treatment with intravenous metronidazole was resumed with a loading dose of 1 g and was continued with 500 mg 8 hourly.
1988 Neurology 38 399/2 We found that a loading dose of barbiturate led to a very prompt, reproducible, and effective cessation of seizure activity.
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