lipodystrophyn.

/ˌlɪpəʊˈdɪstrəfi/

Forms: Also as modern Latin ˌlipodyˈstrophia.

Etymology: < lipo- comb. form² + dystrophy n. at dys- prefix .

Pathology.

Any of various disorders of fat metabolism; intestinal lipodystrophy, a rare disease (usually called Whipple's disease) of uncertain ætiology, chiefly of middle-aged men, presenting with joint pains, steatorrhœa, wasting, and lymph node enlargement; progressive lipodystrophy [translating modern Latin lipodystrophia progressiva (A. Simons 1911, in Zeitschr. f. d. ges. Neurol. u. Psychiatrie (Orig.) V. 36)] , a condition in which there is a progressive loss of subcutaneous fat, usually from the upper half of the body while the lower half retains its fat.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [noun] > lipodystrophy

lipodystrophy1907

1907 G. H. Whipple in Bull. Johns Hopkins Hosp. XVIII. 391/1 In searching for a name to designate this condition great difficulties were encountered. It would seem that no suitable name can be applied to it until the etiological factor is determined. The term Intestinal Lipodystrophy is suggested.

1925 Q. Jrnl. Med. 18 224 Progressive lipodystrophy is a rare disease characterized by symmetrical and progressive loss of subcutaneous fat over the face, neck, arms, thorax, and abdomen, with a relative or absolute abundance of subcutaneous fat over the lower limbs.

1933 Lancet 23 Dec. 1417/1 The blood chemistry in lipodystrophia progressiva is normal.

1946 Lancet 18 May 730/2 There is no satisfactory classification of the lipodystrophies.

1964 Pediatrics 33 609/1 The syndromes of partial and total lipodystrophy have been reviewed... For inclusion in the syndrome of partial lipodystrophy symmetrical loss of fat from the face with or without truncal loss, but with retention of distal adipose depots was required. In total lipodystrophy fat loss was generalized.

1971 Daily Colonist (Victoria, Brit. Columbia) 28 Dec. 2/1 Lipodystrophy means a disturbance in the metabolism of fatty tissue.

Derivatives

ˌlipodyˈstrophic adj.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [adjective] > lipodystrophy

lipodystrophic1925

1925 Q. Jrnl. Med. 18 231 The active stage having ended, the lipodystrophic process becomes stationary.

1946 Lancet 18 May 731/1 I venture to argue how Ziegler's lipodystrophic case might have a similar disturbance of fat-metabolism without an obvious lipæmia.

This entry has not yet been fully updated (first published 1976; most recently modified version published online December 2020).

单词	lipodystrophy
释义	lipodystrophyn. /ˌlɪpəʊˈdɪstrəfi/ Forms: Also as modern Latin ˌlipodyˈstrophia. Etymology: < lipo- comb. form² + dystrophy n. at dys- prefix . Pathology. Any of various disorders of fat metabolism; intestinal lipodystrophy, a rare disease (usually called Whipple's disease) of uncertain ætiology, chiefly of middle-aged men, presenting with joint pains, steatorrhœa, wasting, and lymph node enlargement; progressive lipodystrophy [translating modern Latin lipodystrophia progressiva (A. Simons 1911, in Zeitschr. f. d. ges. Neurol. u. Psychiatrie (Orig.) V. 36)] , a condition in which there is a progressive loss of subcutaneous fat, usually from the upper half of the body while the lower half retains its fat. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [noun] > lipodystrophy lipodystrophy1907 1907 G. H. Whipple in Bull. Johns Hopkins Hosp. XVIII. 391/1 In searching for a name to designate this condition great difficulties were encountered. It would seem that no suitable name can be applied to it until the etiological factor is determined. The term Intestinal Lipodystrophy is suggested. 1925 Q. Jrnl. Med. 18 224 Progressive lipodystrophy is a rare disease characterized by symmetrical and progressive loss of subcutaneous fat over the face, neck, arms, thorax, and abdomen, with a relative or absolute abundance of subcutaneous fat over the lower limbs. 1933 Lancet 23 Dec. 1417/1 The blood chemistry in lipodystrophia progressiva is normal. 1946 Lancet 18 May 730/2 There is no satisfactory classification of the lipodystrophies. 1964 Pediatrics 33 609/1 The syndromes of partial and total lipodystrophy have been reviewed... For inclusion in the syndrome of partial lipodystrophy symmetrical loss of fat from the face with or without truncal loss, but with retention of distal adipose depots was required. In total lipodystrophy fat loss was generalized. 1971 Daily Colonist (Victoria, Brit. Columbia) 28 Dec. 2/1 Lipodystrophy means a disturbance in the metabolism of fatty tissue. Derivatives ˌlipodyˈstrophic adj. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [adjective] > lipodystrophy lipodystrophic1925 1925 Q. Jrnl. Med. 18 231 The active stage having ended, the lipodystrophic process becomes stationary. 1946 Lancet 18 May 731/1 I venture to argue how Ziegler's lipodystrophic case might have a similar disturbance of fat-metabolism without an obvious lipæmia. This entry has not yet been fully updated (first published 1976; most recently modified version published online December 2020). < n.1907
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