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单词 lipidosis
释义

lipidosisn.

Brit. /ˌlɪpᵻˈdəʊsɪs/, U.S. /ˌlɪpəˈdoʊsəs/
Forms: Plural lipidoses.
Etymology: < lipid n. + -osis suffix.
Medicine.
Any disorder characterized by an excessive accumulation of a lipid in certain tissues.
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the world > health and disease > ill health > a disease > diseases of tissue > [noun] > lipidosis
lipoidosis1932
lipidosis1941
sphingolipidosis1962
1941 S. J. Thannhauser Lipidoses i. 2 A summary of the present knowledge..of lipid substances is..an appropriate introduction to the group of diseases, which are called ‘lipoidoses’ or ‘lipidoses’.
1961 R. D. Baker Essent. Pathol. iv. 47 The lipidoses are conditions in which fatty substances collect in macrophages, sometimes as part of the macrophage (reticulo-endothelial) system, sometimes in ectopic clusters of these cells and rarely in other types of cells. These diseases are also termed lipid-storage diseases.
1961 R. D. Baker Essent. Pathol. iv. 49 Niemann-Pick's Disease. This is a truly systemic lipidosis of the macrophage system, occurring typically in infants, with splenomegaly and hepatomegaly.
1966 G. P. Wright & W. S. Symmers Systemic Pathol. I. v. 245/1 Different lipids are concerned in each of the primary lipidoses, a different enzyme failure presumably being characteristic of each disease.
This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2022).
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n.1941
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