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单词 atebrin
释义

atebrinn.

/ˈatɪbrɪn/
Forms: Also (chiefly U.S.) atabrine. (Both are proprietary terms.)
Etymology: < -ate suffix1 1c +brin- (in brine n.).
A synthetic antimalarial drug, quinacrine dihydrochloride; also called mepacrine n.The word is recorded from 1913 but was not applied to the anti-malarial drug discovered by the German chemists H. Mauss and F. Mietzsch in 1930 (when it was known by the laboratory name of ‘Erion’) until 1932. See 1933 Klinische Wochenschrift 19 Aug., 1276–8.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for malaria
Plasmochin1926
Plasmoquine1926
atebrin1932
quinacrine1934
pamaquin1941
Paludrine1944
chloroquine1946
Resochin1946
proguanil1948
primaquine1949
hydroxychloroquine1951
pyrimethamine1952
mefloquine1974
qinghaosu1979
1913 Trade Marks Jrnl. 12 Mar. 390 Atebrin. Chemical Substances Prepared for Use in Medicine and Pharmacy..The Bayer Comp., Limited, Manchester.]
1932 Lancet 16 Apr. 826/1 Atebrin, originally called erion, has been produced recently by the makers of plasmoquine.
1933 Discovery Apr. 118/1 Atebrin, made by the chemists Mietzsch and Mauss..in some experiments..has been more successful than quinine in curing and preventing relapses [of malaria].
1935 F. Stark Let. 17 Mar. in Coast of Incense (1953) i. 91 Decided it must be malaria—took masses of atebrin.
1945 Times 1 Sept. 4/3 The sick had few medical supplies and no quinine or atebrin.
1948 Chem. Abstr. 1937–46 Index 4073/1 Atabrine.
1957 New Yorker 29 June 75/1 The only malaria suppressive available for the Buna campaign was quinine; even atabrine, itself now an outmoded weapon against the disease, was not on hand.
1961 J. Heller Catch-22 (1962) xxxviii. 391 I'm sorry about making such a fuss about those Atabrine tablets on the way over. If you want to catch malaria, I guess it's your business, isn't it?
This entry has not yet been fully updated (first published 1972; most recently modified version published online June 2018).
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n.1932
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