levodopan.
/ˌliːvəˈdəʊpə/, /ˌlɛvəˈdəʊpə/, U.S. /ˌlɛvəˈdoʊpə/ Chemistry and Biochemistry.
The lævorotatory l form of dopa (see L n. 6c and dopa n.).
ΚΠ
1970 Brit. Med. Jrnl. 7 Feb. 331 (heading) Treatment of Parkinsonism with laevo-dopa.
1970 Jrnl. Amer. Med. Assoc. 16 Mar. 1857/3 Levodopa increased the severity of depression.
1971 Lancet 19 June 1272/2 It seems unlikely that levodopa will have a favourable therapeutic effect on acne vulgaris.
1972 Approved Names 1970 (Brit. Pharmacopœia Comm.) Suppl. 1 Levodopa, (−)-3-(3, 4-Dihydroxyphenyl)- l-alanine.
1974 Times 8 Jan. 14/6 The weakness and tremor of Parkinson's disease are thought to be caused by a lack of the chemical dopamine. Treatment with levodopa corrects that deficiency, as the drug is converted to dopamine within the body.
This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2022).
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n.1970