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leuco-taxin
leuco-taxin n.
Brit. 
/ˌl(j)uːkə(ʊ)ˈtaksɪn/
, /ˌl(j)uːkə(ʊ)ˈtaksɪn/U.S. /ˌlukoʊˈtæks(ə)n/
(also leuco-'taxine) [ < Greek τάξις arrangement, order] Physiology a nitrogenous material found in injured tissue and inflammatory exudates which on injection causes inflammation, increase in the permeability of capillaries, and the attraction of leucocytes to the site./ˌlukoʊˈtæks(ə)n/ΘΚΠ
the world > matter > chemistry > organic chemistry > crystalline substances > [noun] > others
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leuco-taxin1937
lotaustralin1938
ionophore1955
1937 V. Menkin in Proc. Soc. Exper. Biol. & Med. 36 167 For the sake of convenience the name leukotaxine is tentatively proposed for this active crystalline nitrogenous substance which is evidently released by injured tissue and is readily recovered in inflammatory exudates.
1947 New Biol. 2 135 The most reasonable hypothesis is..that leucotaxine is released from the killed and damaged cells of the injured skin we are considering, and is mainly responsible for the escape of fluid from nearby undamaged capillaries.
1957 Amer. Jrnl. Physiol. 189 99 (caption) A preliminary intravenous injection of 25 mg of cortisone acetate was performed in the tested rabbit to inactivate the masking effect of any leukotaxine possibly present in the acid exudate to be injected.
1964 W. G. Smith Allergy & Tissue Metabolism iii. 39 This material, which Menkin called leucotaxin, can upon injection into the skin induce increased capillary permeability and chemotactic attraction of polymorphs to the injection site.
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