Letterer–Siwen.

Brit.

/ˌlɛt(ə)rəˈsiːvə/, U.S.

/ˌlɛdərərˈsivə/

Origin: From proper names. Etymons: proper names Letterer, Siwe.

Etymology: < the names of Erich Letterer (1895–1982), German pathologist, and Sture August Siwe (1897–1966), Swedish paediatrician, who described the disorder independently in 1924 ( Frankfurter Zeitschr. f. Pathol. 30 377) and 1933 ( Zeitschr. f. Kinderheilkunde 55 212), respectively.

Medicine.

attributive and in the genitive. Designating a severe form of histiocytosis occurring mainly in infants and young children in which many organs of the body are affected by the proliferation of Langerhans cells.

ΘΚΠ

the world > health and disease > ill health > a disease > diseases of tissue > [adjective] > growth of abnormal tissue > type of

fungating1795

round-celled1867

pseudohypertrophic1868

round-cell1870

homologous1871

paraplastic1896

paraplasmic1901

sarcoid1935

Letterer–Siwe1936

fibrogenic1953

sarcoidal1961

lymphoproliferative1964

1936 A. F. Abt & E. J. Denenholz in Amer. Jrnl. Dis. Children 51 499 (heading) Letterer–Siwe's disease.

1949 Amer. Jrnl. Pathol. 25 49 These cases fulfill the requirements for Letterer–Siwe's disease as formulated by Abt and Denenholz.

1961 R. D. Baker Essent. Pathol. xviii. 489 Reticuloendotheliosis (Letterer–Siwe disease) is either a hyperplasia or a true neoplasm of the macrophage system of infants, with enlargement of the liver and spleen.

1986 Times 13 June 13/2 Doctors have to be on the look-out for..the very rare hystiocytosis [sic] X (Letterer–Siwe disease).

2001 Ottawa Sun (Nexis) 2 June 44 The inappropriate presence of large numbers of histiocytes in organs causes a spectrum of diseases called as a group, histiocytosis X. This group includes Letterer-Siwe disease, Hand-Schuller-Christian disease and eosinophilic granuloma.

This entry has been updated (OED Third Edition, September 2011; most recently modified version published online March 2022).

单词	letterer–siwe
释义	Letterer–Siwen. Brit. /ˌlɛt(ə)rəˈsiːvə/, U.S. /ˌlɛdərərˈsivə/ Origin: From proper names. Etymons: proper names Letterer, Siwe. Etymology: < the names of Erich Letterer (1895–1982), German pathologist, and Sture August Siwe (1897–1966), Swedish paediatrician, who described the disorder independently in 1924 ( Frankfurter Zeitschr. f. Pathol. 30 377) and 1933 ( Zeitschr. f. Kinderheilkunde 55 212), respectively. Medicine. attributive and in the genitive. Designating a severe form of histiocytosis occurring mainly in infants and young children in which many organs of the body are affected by the proliferation of Langerhans cells. ΘΚΠ the world > health and disease > ill health > a disease > diseases of tissue > [adjective] > growth of abnormal tissue > type of fungating1795 round-celled1867 pseudohypertrophic1868 round-cell1870 homologous1871 paraplastic1896 paraplasmic1901 sarcoid1935 Letterer–Siwe1936 fibrogenic1953 sarcoidal1961 lymphoproliferative1964 1936 A. F. Abt & E. J. Denenholz in Amer. Jrnl. Dis. Children 51 499 (heading) Letterer–Siwe's disease. 1949 Amer. Jrnl. Pathol. 25 49 These cases fulfill the requirements for Letterer–Siwe's disease as formulated by Abt and Denenholz. 1961 R. D. Baker Essent. Pathol. xviii. 489 Reticuloendotheliosis (Letterer–Siwe disease) is either a hyperplasia or a true neoplasm of the macrophage system of infants, with enlargement of the liver and spleen. 1986 Times 13 June 13/2 Doctors have to be on the look-out for..the very rare hystiocytosis [sic] X (Letterer–Siwe disease). 2001 Ottawa Sun (Nexis) 2 June 44 The inappropriate presence of large numbers of histiocytes in organs causes a spectrum of diseases called as a group, histiocytosis X. This group includes Letterer-Siwe disease, Hand-Schuller-Christian disease and eosinophilic granuloma. This entry has been updated (OED Third Edition, September 2011; most recently modified version published online March 2022). < n.1936
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