lathyrogenn.

/ˈlaθɪrədʒən/

Etymology: < lathyr- (in lathyrism n.) + -ogen comb. form.

Medicine.

A substance which causes lathyrism.

ΘΚΠ

the world > physical sensation > use of drugs and poison > poison > [noun] > poison affecting the nerves

neurotoxin1902

lathyrogen1962

1962 Lab. Investig. 11 697/1 It has not been proven whether the lesions result from the direct action of the lathyrogen on the cartilage or from the action of some metabolic product of the lathyrogenic agent.

1972 Science 5 May 512/2 Most common among toxic substances are the enzyme inhibitors... Physiological irritants might be the next most common category. These include..the lathyrogens, which disrupt collagen structure and occur in peas.

1978 Nature 11 May 151/2 Direct evidence that the structure of collagen influences morphogenetic events is provided by studies in vivo with lathyrogens such as β-amino-propionitrile, which interfere with the crosslinking of collagen by inhibiting the action of the enzyme lysyl oxidase.

Derivatives

lathyroˈgenic adj.

ΘΚΠ

the world > physical sensation > use of drugs and poison > poison > [adjective] > specific

botulinum1910

pesticidal1937

fungitoxic1945

embryotoxic1949

lathyrogenic1958

scombrotoxic1967

genotoxic1973

1958 Proc. Soc. Exper. Biol. & Med. 97 114/1 Methyleneaminoacetonitrile has also been reported to be strongly lathyrogenic.

1983 Exper. Neurol. 79 102 The first question..is whether the fibrogenic components of the peripheral nerve will be exposed to the lathyrogenic effects of β-APN when it is topically applied.

This entry has not yet been fully updated (first published 1997; most recently modified version published online June 2018).

单词	lathyrogen
释义	lathyrogenn. /ˈlaθɪrədʒən/ Etymology: < lathyr- (in lathyrism n.) + -ogen comb. form. Medicine. A substance which causes lathyrism. ΘΚΠ the world > physical sensation > use of drugs and poison > poison > [noun] > poison affecting the nerves neurotoxin1902 lathyrogen1962 1962 Lab. Investig. 11 697/1 It has not been proven whether the lesions result from the direct action of the lathyrogen on the cartilage or from the action of some metabolic product of the lathyrogenic agent. 1972 Science 5 May 512/2 Most common among toxic substances are the enzyme inhibitors... Physiological irritants might be the next most common category. These include..the lathyrogens, which disrupt collagen structure and occur in peas. 1978 Nature 11 May 151/2 Direct evidence that the structure of collagen influences morphogenetic events is provided by studies in vivo with lathyrogens such as β-amino-propionitrile, which interfere with the crosslinking of collagen by inhibiting the action of the enzyme lysyl oxidase. Derivatives lathyroˈgenic adj. ΘΚΠ the world > physical sensation > use of drugs and poison > poison > [adjective] > specific botulinum1910 pesticidal1937 fungitoxic1945 embryotoxic1949 lathyrogenic1958 scombrotoxic1967 genotoxic1973 1958 Proc. Soc. Exper. Biol. & Med. 97 114/1 Methyleneaminoacetonitrile has also been reported to be strongly lathyrogenic. 1983 Exper. Neurol. 79 102 The first question..is whether the fibrogenic components of the peripheral nerve will be exposed to the lathyrogenic effects of β-APN when it is topically applied. This entry has not yet been fully updated (first published 1997; most recently modified version published online June 2018). < n.1958
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