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单词 autoregulation
释义

autoregulationn.

Brit. /ˌɔːtə(ʊ)rɛɡjᵿˈleɪʃn/, U.S. /ˌɔdəˌrɛɡ(j)əˈleɪʃ(ə)n/, /ˌɔdoʊˌrɛɡ(j)əˈleɪʃ(ə)n/, /ˌɑdəˌrɛɡ(j)əˈleɪʃ(ə)n/, /ˌɑdoʊˌrɛɡ(j)əˈleɪʃ(ə)n/
Origin: Formed within English, by compounding. Etymons: auto- comb. form1, regulation n.
Etymology: < auto- comb. form1 + regulation n. Compare French autorégulation (1887 or earlier). Compare earlier self-regulation n. and later autoregulate v.
1. Regulation of a system or process by itself or from within, esp. in such a way as to maintain a stable state; = self-regulation n. 2
ΚΠ
1889 Physician & Surgeon Apr. 163 The insufficiency of the heart follows nutritive difficulties, the auto-regulation cannot furnish a sufficient force for a prolonged time.
1908 Jrnl. Amer. Chem. Soc. 30 1011 The secretion of the enzyme into the surrounding medium is a function of the living cell, being made possible by autoregulation of the permeability of the protoplasmic cell wall.
1935 N. Fialko Passivity & Rationalization iii. 202 The ideas..may prove sound and effective in the autoregulation of the supply of works of art commensurable with the needs of existing society.
1966 Proc. 3rd Internat. Conf. Hyperbaric Med. iii. 227/1 If..arterial pressure goes up or down, autoregulation prevents marked change in the blood flow despite the pressure change.
2007 F. Shearer Power Managem. Mobile Devices v. 176 To take advantage of backlight autoregulation, a mobile device must be equipped with a photo sensor to detect the ambient luminance.
2. Genetics. Regulation of the expression of a gene by a product of that gene.
ΚΠ
1969 Jrnl. Bacteriol. 97 1375 (title) Autoregulation of the synthesis of nitrate reductase in Aspergillus nidulans.
1971 D. J. Cove Genetics xi. 168 This direct feedback by which the amount of product of a gene controls the synthesis of that gene product has been called autoregulation.
1993 Cell 73 286/2 One feature of the Drosophila Dfd gene is that autoregulation plays an important role in maintaining some aspects of its normal expression pattern.
2005 S. R. Kushner in N. P. Higgins Bacterial Chromosome xviii. 336/1 Many of the genes involved in mRNA decay..are controlled in part by autoregulation.
This is a new entry (OED Third Edition, June 2011; most recently modified version published online December 2021).
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n.1889
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