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单词 a-dna
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A-DNA
13. Biochemistry. Denoting a form of double stranded nucleic acid comprising a right-handed double helix in which the base pairs form an angle of approximately seventy degrees with the helix axis; (also) designating DNA or RNA forming this structure; esp. in A-DNA. Cf. B n. Additions.This structure occurs commonly in double stranded RNA and DNA-RNA hybrids, but in DNA it is found only under conditions of low relative humidity or high salt concentration.
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nucleoproteid1886
nucleic acid1892
nucleoprotein1906
A1953
genophore1961
1953 R. E. Franklin & R. G. Gosling in Nature 25 Apr. 740/1 Sodium Thymonucleate fibres give two distinct types of X-ray diagram. The first corresponds to a crystalline form, structure A, obtained at about 75 per cent relative humidity... At higher humidities a different structure, structure B, showing a lower degree of order, appears and persists over a wide range of ambient humidity. The change from A to B is reversible.
1974 Jrnl. Molecular Biol. 88 524 We prepared specimens of D-DNA under the minimum retained salt conditions that would normally yield an A-DNA.
1988 P. W. Kuchel et al. Schaum's Outl. Theory & Probl. Biochem. vii. 185 This is a result of a change to the A form, in which the base pairs are not perpendicular to the helix axis.
2005 D. P. Clark Molecular Biol. iv. 92 Double-stranded RNA or hybrids with one RNA and one DNA strand usually form an A-helix.
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