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单词 l-form
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L-form
c. Bacteriology. [L said to be < the Lister Institute, where Klieneberger worked.] The designation (now usually as L-form) of an atypical form of certain bacteria which arises from and usually reverts to the normal form but is sometimes stable, and which lacks a cell wall, exhibits a very variable shape, and somewhat resembles a mycoplasma.
ΚΠ
1935 E. Klieneberger in Jrnl. Pathol. & Bacteriol. 40 93 These swollen elements [among the bacillary chains of Streptobacillus moniliformis], with an associated fine mycelial system resembling that of pleuropneumonia and agalactia, constitute an independent colonial system containing all strains of S. moniliformis so far examined. A delicate streptococcus has also been recovered..from the nasopharynx of healthy guinea-pigs harbouring a similar pleuropneumonia-like symbiont. These two pleuropneumonia-like organisms in association respectively with S. moniliformis and a streptococcus..will be referred to..simply as L1 and L2 pending the coining of appropriate generic names.
1950 C. E. Clifton Introd. Bacteria vi. 132 Streptobacillus moniliformis..resembles the actinomyces in many respects but gives rise after several days' incubation to highly pleomorphic forms characteristic of the pleuropneumonia group... Present evidence indicates that there is but one organism involved and that the actinomyces-like form and the L1 form represent different stages of growth of one organism characterized by a complex reproductive cycle.
1968 Zinsser Microbiol. (ed. 14) lii. 794/2 Some L phase mutants revert back to normal size organisms as soon as the penicillin is removed from the medium. Others are stable in the L phase on solid media but revert back when subcultured in broth.
1973 J. Levy et al. Introd. Microbiol. ii. 39 Because they did not have a wall, they were not affected by penicillin or other antibiotics that interfere with cell wall synthesis. The mutation to an L-form is therefore troublesome if the bacterium is a pathogen.
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