kallidinn.

/ˈkalɪdɪn/

Etymology: < German kallidin (E. Werle 1948, in Angew. Chem. LX. a. 53), < German kall-ikrein kallikrein n. + pept-id peptide n.: see -in suffix¹.

Biochemistry.

†a. A supposed hypotensive peptide, released from a globulin by the enzyme kallikrein, which stimulates the uterus and intestine; later shown to be a mixture of two such peptides, bradykinin and kallidin (sense b). Obsolete.

ΚΠ

1950 Chem. Abstr. 44 5476 Kallidin (previously called DK substance) is a low-mol.-wt. peptide.

1959 New Scientist 16 Apr. 856/1 When its properties were studied, bradykinin showed itself to be extremely similar to the peptide kallidin, whose existence was first demonstrated in Germany between the wars.

b. (Also kallidin II.) The peptide having the same sequence of constituent amino-acids as bradykinin except for an additional lysergic acid residue at the hydrogen end.

ΚΠ

1961 Pierce & Webster in Biochem. & Biophysical Res. Communications V. 353 The present report describes the isolation of two kallidins from the incubation of human urinary kallikrein with acid-treated human plasma.

1961 Pierce & Webster in Biochem. & Biophysical Res. Communications V. 354 Two peaks of activity [on a chromatograph] were obtained. These were designated kallidins I and II.

1961 Pierce & Webster in Biochem. & Biophysical Res. Communications V. 356 These data indicate that kallidin I is identical with bradykinin and that kallidin II is a decapeptide.

1965 Jrnl. Physiol. 176 1 Bradykinin and kallidin II are respectively, a nona- and a deca-peptide, which occur in man and other species... Kallidin II (hereafter referred to as kallidin), which is converted from kallidinogen by the enzyme kallikrein, appears to be the immediate precursor of bradykinin.

1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xvii. 1 The name kallidin now refers specifically to lysyl-bradykinin.

This entry has not yet been fully updated (first published 1976; most recently modified version published online September 2018).

单词	kallidin
释义	kallidinn. /ˈkalɪdɪn/ Etymology: < German kallidin (E. Werle 1948, in Angew. Chem. LX. a. 53), < German kall-ikrein kallikrein n. + pept-id peptide n.: see -in suffix¹. Biochemistry. †a. A supposed hypotensive peptide, released from a globulin by the enzyme kallikrein, which stimulates the uterus and intestine; later shown to be a mixture of two such peptides, bradykinin and kallidin (sense b). Obsolete. ΚΠ 1950 Chem. Abstr. 44 5476 Kallidin (previously called DK substance) is a low-mol.-wt. peptide. 1959 New Scientist 16 Apr. 856/1 When its properties were studied, bradykinin showed itself to be extremely similar to the peptide kallidin, whose existence was first demonstrated in Germany between the wars. b. (Also kallidin II.) The peptide having the same sequence of constituent amino-acids as bradykinin except for an additional lysergic acid residue at the hydrogen end. ΚΠ 1961 Pierce & Webster in Biochem. & Biophysical Res. Communications V. 353 The present report describes the isolation of two kallidins from the incubation of human urinary kallikrein with acid-treated human plasma. 1961 Pierce & Webster in Biochem. & Biophysical Res. Communications V. 354 Two peaks of activity [on a chromatograph] were obtained. These were designated kallidins I and II. 1961 Pierce & Webster in Biochem. & Biophysical Res. Communications V. 356 These data indicate that kallidin I is identical with bradykinin and that kallidin II is a decapeptide. 1965 Jrnl. Physiol. 176 1 Bradykinin and kallidin II are respectively, a nona- and a deca-peptide, which occur in man and other species... Kallidin II (hereafter referred to as kallidin), which is converted from kallidinogen by the enzyme kallikrein, appears to be the immediate precursor of bradykinin. 1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xvii. 1 The name kallidin now refers specifically to lysyl-bradykinin. This entry has not yet been fully updated (first published 1976; most recently modified version published online September 2018). < n.1950
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