ionotropicadj.1
/ˌʌɪənəˈtrɒpɪk/, /ˌʌɪənəˈtrəʊpɪk/, U.S. /ˌaɪənəˈtrɑpɪk/ 1. Chemistry. Exhibiting or relating to the form of tautomerism called ionotropy (ionotropy n.1 1). rare.
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1934 R. F. Hunter Electronic Theory Chem. xi. 111 One of the most valuable applications of the ionotropic theory of tautomerism..is to the problem of the addition of bromine and hydrogen to conjugated compounds of the butadiene type.
2005 J. Maier in B. E. Conway Mod. Aspects Electrochem. No. 38 i. 41 It is even possible to transform the Brønsted-concept in its ionotropic generalization to solids.
2. Physical Chemistry. Of a gel or its particles: exhibiting ionotropy (ionotropy n.1 2); of or relating to such a gel.
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the world > matter > chemistry > ions, ionization, or electrolysis > [adjective] > exhibiting ionotropy
ionotropic1944
1944 Handbk. Descr. in Chem. & Chem. Engin. (U.S. Manpower Comm.) Nov. 66 Polarity, ionotropic change and conjugation.
1954 H. Thiele in Discuss. Faraday Soc. 18 295 Since ionotropic gels are formed by chemical or electrical forces the degree of order decreases with decreasing dissociation of the ionic groups of the colloid particles.
1969 Jrnl. Biomed. Materials Res. 3 432 The ordered ionotropic structure of the fibers of the polyelectrolyte directs the mineralization and calcification in the same manner as in biological tissue.
2009 I. Donati & S. Paoletti in B. H. A. Rehm Alginates 31 The treatment of an alginate semidilute solution..with a proper divalent cation, i.e., Ca2+, results in the formation of a ionotropic (lyotropic) gel.
3. Physiology. Designating a neurotransmitter that functions by altering the flow of ions across the cell membrane of the postsynaptic cell; designating a cell receptor whose effect is mediated in this way; relating to or involving such receptors. Cf. metabotropic adj.
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1978 P. L. McGeer et al. Molecular Neurobiol. Mammalian Brain ii. 141 Neurotransmitters..fall into two categories. The first we refer to as ionotropic because the principal function of the transmitter is to open ionic paths across the postsynaptic membrane.
1989 Proc. National Acad. Sci. U.S.A. 86 4316/1 The putative transmitter of the climbing [nerve] fibers, l-aspartate, enhances calcium permeability via ionotropic receptors.
2006 G. Buzsáki Rhythms of Brain ix. 249 Excitation of interneurons by pyramidal cells can be readily prevented in slice preparations by blocking the ionotropic glutamate receptors by appropriate drugs.
2008 Respiratory Physiol. & Neurobiol. 164 18/2 Most neurons in the brain use glutamate, GABA, and/or glycine as their major ionotropic neurotransmitter.
This entry has been updated (OED Third Edition, March 2012; most recently modified version published online March 2022).
ionotropicadj.2
/ˌʌɪənəˈtrɒpɪk/, /ˌʌɪənəˈtrəʊpɪk/, U.S. /ˌaɪənəˈtrɑpɪk/ Physiology.
= inotropic adj.
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the world > life > the body > structural parts > muscle > [adjective] > muscular tension
tonical1586
tonic1649
inotropic1903
ionotropic1939
1939 Jrnl. Allergy 10 406 One per cent histamine produced marked ionotropic and chronotropic effects in the isolated heart.
1970 G. A. Langer in F. H. Adams et al. Pathophysiol. Congenital Heart Dis. 181 Those mechanisms which are positively ionotropic but would not meet the definition of increased contractility..do not involve increments in calcium uptake.
2010 Heart, Lung, & Circulation 19 613/1 The patient was transferred to intensive care on minimal ionotropic support.
This is a new entry (OED Third Edition, March 2012; most recently modified version published online March 2022).
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