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单词 artificial chromosome
释义

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artificial chromosome
artificial chromosome n. Biology (originally) a synthetic nucleic acid sequence designed to mimic the structure and behaviour of a chromosome; (now usually) a nucleic acid sequence into which an artificial or modified gene, or a fragment of a natural genome which is being studied, can be maintained, reproduced, and manipulated within a carrier such as a bacterial or yeast cell.
ΚΠ
1983 Nature 15 Sept. 189 Fifty-five-kilobase long artificial chromosomes containing cloned genes, replicators, centromeres and telomeres have been constructed in yeast.
1999 Independent 10 Dec. i. 5/1 The next stage is to synthesise the genes by machine, insert them into an artificial chromosome and add it to a chemical ‘soup’ in which the genes can begin to orchestrate the replication of a novel life-form.
2002 Science 6 Sept. 1638/2 Bacterial artificial chromosomes (BACs) for detailed genetic studies of neglected species..are useful for storing and cataloging DNA.
extracted from artificialadj.n.
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