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单词 hypertensin i
释义

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hypertensin I
Either of two polypeptides, of which one ( hypertensin I) is formed in the blood by the action of renin on a protein (hypertensinogen), and the other ( hypertensin II) is derived from it by the loss of two amino-acid residues, causes a rise in blood pressure, and stimulates the secretion of aldosterone; also, analogous polypeptides in animals. Now usually called angiotensin.
ΚΠ
1939 J. M. Muñoz et al. in Nature 9 Dec. 980/1 This substance, which we name hypertensin, is different from adrenalin, tyramin, pitressin and urohypertensin.
1954 L. T. Skeggs et al. in Jrnl. Exper. Med. 99 282 Two types of hypertensin have been demonstrated... The first type..has been designated hypertensin I. It can be rapidly converted to a second, approximately equally pressor compound, hypertensin II.
1956 Nature 17 Mar. 527/2 The isolation and purification of a hypertensin peptide, resulting from the action of rabbit renin on ox serum.
1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin I preparations of slightly different composition have been described, depending on the sources of the renin and the substrate used.
1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin has also been called angiotonin. A uniform nomenclature has been proposed which would designate this compound as angiotensin.
extracted from hypertensinn.
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