hypertensinn.

/hʌɪpəˈtɛnsɪn/

Etymology: < hypertens- (in hypertension n., hypertensive adj.) + -in suffix¹.

Biochemistry.

Either of two polypeptides, of which one ( hypertensin I) is formed in the blood by the action of renin on a protein (hypertensinogen), and the other ( hypertensin II) is derived from it by the loss of two amino-acid residues, causes a rise in blood pressure, and stimulates the secretion of aldosterone; also, analogous polypeptides in animals. Now usually called angiotensin.

ΚΠ

1939 J. M. Muñoz et al. in Nature 9 Dec. 980/1 This substance, which we name hypertensin, is different from adrenalin, tyramin, pitressin and urohypertensin.

1954 L. T. Skeggs et al. in Jrnl. Exper. Med. 99 282 Two types of hypertensin have been demonstrated... The first type..has been designated hypertensin I. It can be rapidly converted to a second, approximately equally pressor compound, hypertensin II.

1956 Nature 17 Mar. 527/2 The isolation and purification of a hypertensin peptide, resulting from the action of rabbit renin on ox serum.

1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin I preparations of slightly different composition have been described, depending on the sources of the renin and the substrate used.

1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin has also been called angiotonin. A uniform nomenclature has been proposed which would designate this compound as angiotensin.

Derivatives

ˌhypertenˈsinogen n. [ < French hypertensinogène (E. Braun-Menendez 1940, in Compt. Rend. de la Soc. de Biol. CXXXIV. 489): see -ogen comb. form] a globulin produced by the liver and present in blood, from which hypertensin I may be liberated by renin.

ΘΚΠ

the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > red cells or corpuscles > haemoglobin > forms or parts of

globulin1831

haematosin1834

haemato-crystallin1865

oxyhaemoglobin1869

methaemoglobin1870

globin1872

haematogen1890

methaemoglobulin1890

haemagglutinin1904

haem1925

hypertensinogen1941

angiotensinogen1958

1941 Amer. Jrnl. Physiol. 135 214 Braun-Menendez has preferred the term hypertensinogen, which implies that it is the substrate on which renin acts.

1965 New Scientist 25 Nov. 561/3 Kidney cells, in the presence of a poor blood flow.., secreted an enzyme called renin which converted a normal constituent of plasma (hypertensinogen) into a new substance (hypertensin).

This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2019).

单词	hypertensin
释义	hypertensinn. /hʌɪpəˈtɛnsɪn/ Etymology: < hypertens- (in hypertension n., hypertensive adj.) + -in suffix¹. Biochemistry. Either of two polypeptides, of which one ( hypertensin I) is formed in the blood by the action of renin on a protein (hypertensinogen), and the other ( hypertensin II) is derived from it by the loss of two amino-acid residues, causes a rise in blood pressure, and stimulates the secretion of aldosterone; also, analogous polypeptides in animals. Now usually called angiotensin. ΚΠ 1939 J. M. Muñoz et al. in Nature 9 Dec. 980/1 This substance, which we name hypertensin, is different from adrenalin, tyramin, pitressin and urohypertensin. 1954 L. T. Skeggs et al. in Jrnl. Exper. Med. 99 282 Two types of hypertensin have been demonstrated... The first type..has been designated hypertensin I. It can be rapidly converted to a second, approximately equally pressor compound, hypertensin II. 1956 Nature 17 Mar. 527/2 The isolation and purification of a hypertensin peptide, resulting from the action of rabbit renin on ox serum. 1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin I preparations of slightly different composition have been described, depending on the sources of the renin and the substrate used. 1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin has also been called angiotonin. A uniform nomenclature has been proposed which would designate this compound as angiotensin. Derivatives ˌhypertenˈsinogen n. [ < French hypertensinogène (E. Braun-Menendez 1940, in Compt. Rend. de la Soc. de Biol. CXXXIV. 489): see -ogen comb. form] a globulin produced by the liver and present in blood, from which hypertensin I may be liberated by renin. ΘΚΠ the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > red cells or corpuscles > haemoglobin > forms or parts of globulin1831 haematosin1834 haemato-crystallin1865 oxyhaemoglobin1869 methaemoglobin1870 globin1872 haematogen1890 methaemoglobulin1890 haemagglutinin1904 haem1925 hypertensinogen1941 angiotensinogen1958 1941 Amer. Jrnl. Physiol. 135 214 Braun-Menendez has preferred the term hypertensinogen, which implies that it is the substrate on which renin acts. 1965 New Scientist 25 Nov. 561/3 Kidney cells, in the presence of a poor blood flow.., secreted an enzyme called renin which converted a normal constituent of plasma (hypertensinogen) into a new substance (hypertensin). This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2019). < n.1939
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