单词 | idebenone |
释义 | idebenonen. Pharmacology. A synthetic antioxidant which is an analogue of coenzyme Q, used in skin care preparations and in the (mostly experimental) treatment of disorders associated with increased oxidative stress.Idebenone is a quinone with a long alkyl side chain. Systematic name: 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone, C19H30O5. ΚΠ 1984 M. Suno & A. Nagaoka in Japanese Jrnl. Pharmacol. 35 196 (title) Inhibition of lipid peroxidation by a novel compound, idebenone (CV-2619). 1990 Washington Post (Nexis) 24 July z5 For the past two years, doctors in Japan and parts of Europe have used the drug—idebenone—to treat strokes. 1996 L. Shihabuddin & K. L. Davis in Z. S. Khachaturian & T. S. Radebaugh Alzheimer's Dis. xxii. 265 Vitamin E and idebenone are also potential antioxidants for treatment of Alzheimer's disease since they prevent cell death caused by glutamate and amyloid beta protein. 2005 Independent 14 Mar. (Review section) 9/5 I would recommend applying a good sun-protection cream in the morning, and then using the idebenone once the sunscreen has fully dried. This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022). < n.1984 |
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