hypophysialadj.

1882 Jrnl. Linn. Soc.: Zool. 16 133 In the Mammalian series I have to observe that, in the lower and smaller members, as the brain loses in relative size and complexity, the pineal or conarial and pituitary or hypophysial bodies and connections show a relatively larger size.

1893 Jrnl. Pathol. & Bacteriol. 1 360 In the dog there is a more or less symmetrical lateral arrangement of the hypophyseal fissures.

1909 H. Cushing in Jrnl. Amer. Med. Assoc. 24 July 254/1 Symptoms of hypophyseal origin doubtless occur in association with many diseases in which they are overlooked.

1912 H. Cushing Pituitary Body & its Disorders iii. 233 In clinical conditions of hypophyseal deficiency somnolence is a conspicuous feature.

1943 G. W. Corner in Science 15 Jan. 68 In the 1864 revision of Webster..epiphyseal appears before epiphysial; in the revision of 1909 apophyseal enters the lists; in the current (1934) revision hypophyseal appears, and the spelling with -eal is preferred in all three cases... Possibly ‘epiphyseal’ goes back to the days when the noun was often written ‘epiphyse’, or possibly some writers thought it was advisable to make the adjectives from the genitives of the Greek nouns (e.g., epiphyseos, hypophyseos). Much more likely, however, the spelling has been influenced by an American trend in the pronunciation... At the present time (and as far as my observation goes, for decades past) American speakers almost universally place the primary accent on the fourth syllable, e.g., hypophyséal... In spite of the fact that ‘-eal’ is philologically irregular, I make bold to suggest that it be adopted as standard in American scientific writing,..in conformity with our well-nigh general pronunciation of the three words in question.

1955 G. W. Harris Neural Control Pituitary Gland v. 124 The pathway by which a stimulus passes from the hypothalamus to the anterior pituitary appears to be by means of the hypophysial portal vessels.

1962 Gray's Anat. (ed. 33) 1038 The hypophysis receives its blood supply from the internal carotid artery through a superior and an inferior hypophyseal artery on each side.