| 单词 | hutchinson–gilford progeria |
| 释义 | > as lemmasHutchinson–Gilford progeria 1. More fully Hutchinson–Gilford progeria, Hutchinson–Gilford progeria syndrome. A rare syndrome affecting children, beginning in the first year of life and characterized by growth retardation and signs usually associated with ageing, such as wrinkling of the skin, alopecia, severe atherosclerosis, and osteoporosis, and typically resulting in death from cardiovascular disease before the age of twenty. ΘΚΠ the world > health and disease > ill health > a disease > disorders associated with age > [noun] > progeria progeria1904 1904 H. Gilford in Practitioner Aug. 210 The name progeria, for which I am indebted to Mr. James Rhoades and Professor Arthur Sidgwick, is not only a far better word [than micromegaly], but is a true description of the distinguishing features of the two cases. 1927 Times (Weekly ed.) 28 Apr. 475/2 Cases of premature senility in children (goblins) described as progeria, the persistence in an adult (ateleioses) of child characters (elves). 1968 Amer. Jrnl. Roentgenol. Radium Ther. Nucl. Med. 103 173 (title) Progeria. Hutchinson-Gilford syndrome. 1987 D. Hall Seasons at Eagle Pond iv. 72 It is not earned and appropriate aging but disease, acid, blight..—mocking the splendor of Autumn as progeria, wretched aging-disease of children, mocks residents of the nursing home. 1993 Mech. Ageing Dev. 70 163 Elastin and type IV collagen production are markedly elevated in fibroblasts derived from the skin of patients with Hutchinson-Gilford progeria. 2003 Jewish Telegr. (Scotl. ed.) 31 Dec. (World Scene) p. v The boys are victims of Huntington–Gilford Progeria syndrome—an extremely rare genetic disease that accelerates the ageing process to about seven times the normal rate. < as lemmas |
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