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holocrine
holocrine adj. 
/ˈhɒlə(ʊ)krɪn/, /ˈhoʊləkrən/, /ˈhɑləˌkrin/, /ˈhoʊləˌkrin/, /ˈhɑləˌkraɪn/, /ˈhoʊləˌkraɪn/ [ < French olocrine (L. Ranvier 1887, in Jrnl. de Micrographie XI. 9), < Greek κρίνειν to separate] Physiology of, pertaining to, or designating a gland in which the secretion is produced by the complete disintegration of its cells.
Brit. /ˈhɒlə(ʊ)krʌɪn/
, /ˈhɒlə(ʊ)krʌɪn//ˈhɒlə(ʊ)krɪn/U.S. /ˈhɑləkrən/
, /ˈhɑləkrən//ˈhoʊləkrən//ˈhɑləˌkrin//ˈhoʊləˌkrin//ˈhɑləˌkraɪn//ˈhoʊləˌkraɪn/ΘΚΠ
the world > life > the body > secretory organs > gland > types of gland > [adjective]
pituita1598
pituitary1615
lymphatic1649
conglomerated1656
conglobate1666
conglomerate1666
conglobated1676
lymphic1681
conglobulate1709
sudoriferous1713
sudorific1721
sebaceous1728
trajectory1747
cryptal1754
cryptous1804
muciparous1825
racemose1834
racemiform1837
ganglionary1842
muciferous1842
sudoriparous1851
sebiparous1853
racemous1854
sebiferous1858
perilymphangial1873
lymphadenoid1877
perilymphatic1877
mucigenous1881
pituital1890
tubuloracemosec1900
acinic1903
holocrine1905
merocrine1905
exocrine1911
endocrine1914
endocrinic1914
endocrinous1914
endocrinal1923
apocrine1926
eccrine1931
psychoendocrine1946
acinar1949
nodal1954
mucigenic1965
1905 G. M. Gould Dict. New Med. Terms 296/1 Holocrine, applied to a gland the cell of which, after having elaborated the material of secretion, falls into disuse and disappears.
1928 E. V. Cowdry Special Cytol. I. ii. 36 In the sebaceous glands the secretory products are elaborated by the fatty metamorphosis, destruction and discharge of the cells themselves. These are the ‘holocrine’ glands of Ranvier.
1939 V. B. Wigglesworth Princ. Insect Physiol. xi. 264 In Orthoptera, secretion is merocrine during continuous small meals, holocrine when a meal follows a period of fasting.
1949 Gray's Anat. (ed. 30) 1254 As the sebaceous glands produce their secretion by complete fatty degeneration of their central cells they are classed as holocrine glands.
1961 E. H. Mercer Keratin & Keratinization ii. 59 Some cutaneous holocrine glands of reptiles..are sac-like invaginations of the epidermis producing fatty materials.
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