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单词 homogentisic
释义

homogentisicadj.

/hɒməʊdʒɛnˈtɪsɪk/
Etymology: translating German homogentisinsäure homogentisic acid (Wolkow & Baumann 1891, in Zeitschr. f. Physiol. Chem. XV. 245), < homodynamous adj. (b) at homo- comb. form 1 + gentisic adj.
homogentisic acid n. a crystalline compound, C8H8O4, which oxidizes to a black compound in air, is an intermediate in the metabolism of aromatic amino-acids, and is excreted in large amounts by persons with alkaptonuria; alkapton, 2,5-dihydroxyphenylacetic acid.
ΘΚΠ
the world > matter > chemistry > organic chemistry > substances from animals or humans > [noun] > substances in urine > miscellaneous others
melanurin1844
kyestein1846
indican1859
heteroxanthine1886
homogentisic acid1891
urobilinogen1893
uroporphyrin1924
uroporphyrinogen1924
pyridoxic acid1944
1891 Jrnl. Chem. Soc. 60 1129 These [crystals] consisted of a substance very similar to, but not identical with, Kirk's uroleucic acid, and the name homogentisic acid is given to it.
1942 Jrnl. Amer. Med. Assoc. 11 July 882/1 Homogentisic acid isolated from one of the positive urines itself gave a strongly positive reaction.
1969 Listener 16 Jan. 74/3 It's now known that not only do one's genes decide whether one is to have red hair, double-jointed thumbs or a Hapsburg lip, but they also decide whether one is going to excrete homogentisic acid or not.
1970 C. N. Graymore Biochem. Eye vii. 478 Phenylalanine and tyrosine are converted through quinone intermediates to homogentisic acid.

Derivatives

homoˈgentisate n. a salt or ester of this acid.
ΘΚΠ
the world > matter > chemistry > organic chemistry > salts, esters or anions of organic acids > [noun]
hydrochloride1823
isethionates1838
citraconate1840
adipate1841
anthranilate1841
stearate1841
itaconic acid1842
salicylate1842
oenanthate1845
ammelide1846
pelargonate1848
pelargyl1851
melanuric acid1852
methylate1852
opianyl1852
abietate1853
maleate1853
fulminuric1856
glyoxylate1856
urethane1856
indican1859
oxalyl1859
malonate1862
methacrylate1865
amylate1866
acetoacetate1873
isobutyrate1873
glutamate1876
hydrobromide1877
nicotinate1879
isovalerate1882
calcium gluconate1884
methoxide1885
isophthalate1886
homogentisate1891
naphthenate1899
peracetate1901
iodoacetate1902
glucuronate1904
hydnocarpate1905
thiomalate1905
azide1907
phytate1908
linolenate1909
isocitrate1925
phenylpyruvate1926
monosodium glutamate1929
perester1933
phosphonate1934
polymethacrylate1935
pantothenate1938
phosphoenolpyruvate1941
nylon salt1945
pantoate1945
penicilloate1946
thymidylate1959
chorismate1965
nonanoate1965
neuraminate1970
1891 Jrnl. Chem. Soc. 60 1129 Lead homogentisate, (C8H7O4)2Pb + 3H2O, crystallises in colourless, brilliant, transparent needles and prisms.
1961 Lancet 5 Aug. 320/1 The homogentisate level in body fluids and urine.
This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2018).
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adj.1891
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