hexobarbitonen.
/hɛksəʊˈbɑːbɪtəʊn/ Pharmacology.
A short-acting barbiturate, C12H16N2O3, with hypnotic properties; also known by proprietary names, as Evipal, Evipan; loosely, = hexobarbitone sodium n. the monosodium derivative of hexobarbitone, a very short-acting and soluble anæsthetic usually given intravenously or intramuscularly; also called hexobarbitone soluble.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > hypnotic > specific drugs
codeine1833
codeia1834
chloral1838
paraldehyde1857
hypnone1886
chloralamide1889
sulphonal1889
uralium1889
ural1891
thymacetin1892
chloralose1893
chloretone1899
hedonal1900
veronal1903
Medinal1908
barbitone1914
barbital1919
Sedormid1928
benzodiazepine1934
hexobarbital1941
hexobarbitone1941
glutethimide1955
Placidyl1955
Mogadon1956
chlordiazepoxide1960
nitrazepam1965
flurazepam1968
medazepam1968
lorazepam1969
Rohypnol1971
flunitrazepam1973
triazolam1973
methapyrilene1974
Halcion1975
the world > health and disease > healing > medicines or physic > medicines for specific purpose > anaesthetic > [noun] > general > specific drugs
common ether1675
laughing gas1819
chloral1838
chloroform1838
urethane1838
ether1847
letheon1847
kerosolene1861
gas1868
pental1891
tubocurarine1898
chloretone1899
hedonal1900
Avertin1927
Evipan1932
Pentothal1935
Trilene1935
hexobarbitone sodium1941
hexobarbitone soluble1941
thiopentone1945
thiopental sodium1947
fluothane1955
halothane1957
methohexital sodium1958
phencyclidine1959
methohexitone1961
hexobarbitone1962
propanidid1964
etorphine1966
enflurane1971
sodium methohexital1978
1941 Brit. Pharmacopœia 1932 (Add. 3) 8 (heading) Hexobarbitonum... Hexobarbitone. Synonym. Hexobarbital... Hexobarbitone is 5-Δ′-cyclohexenyl-5-methyl-N-methyl-barbituric acid.
1943 Brit. Med. Jrnl. 5 June 714/2 Hexobarbitone given by mouth is an excellent hypnotic when there is no pain.
1943 Brit. Med. Jrnl. 20 Nov. 646/1 Cyanosis rapidly became extreme; 0·5 g. of hexobarbitone soluble (evipan sodium) was dissolved in 5 c.cm. of distilled water and administered intravenously.
1952 Martindale's Extra Pharmacopœia (ed. 23) I. 260 Hexobarbitone sodium has largely been superseded by thiopentone sodium which gives greater muscular relaxation.
1962 J. H. Burn Drugs, Med. & Man ix. 98 The substance hexobarbitone could be injected into a vein and the patient went to sleep with no more warning than he had when going to sleep in his own bed.
This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2021).
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n.1941