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单词 homatropine
释义

homatropinen.

Brit. /həʊˈmatrəpiːn/, /həʊˈmatrəpɪn/, U.S. /hoʊˈmætrəpin/
Forms: 1800s– homatropin, 1800s– homatropine.
Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: homo- comb. form, atropine n.
Etymology: < homo- comb. form + atropine n., after German Homatropin (A. Ladenburg 1880, in Berichte der Deutsch. Chem. Gesellsch. 13 107).
Pharmacology.
A synthetic alkaloid related to atropine, used mainly to dilate the pupil of the eye.Homoatropine is the tropine ester of mandelic acid. Formula: C16H21NO3.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > medicine composed of a plant > [noun] > alkaloids
belladonna1788
bebeerine1851
sparteine1851
physostigmine1864
bebeeria1874
pilocarpine1875
hydrastine1876
atropine1877
eserine1879
homatropine1880
ergocryptine1944
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the eyes
eye salveeOE
collyrie1382
collyriuma1398
oculus lucidusc1425
powder of welcome?1541
collyre1562
eye-water?1593
ophthalmic1650
celestial water1739
eye lotion1797
eserine1879
homatropine1880
eye drop1938–9
tropicamide1961
1880 Jrnl. Chem. Soc. 38 410 Homatropine aurochloride..forms first as an oil, which becomes crystalline on standing.
1881 Med. Bull. 3 127/1 Lately a new mydriatic has been added to ophthalmic therapeutics, by the discovery of homatropin.., made in the beginning of 1880, by Prof. Ladenburg, of Kiel.
1901 T. Sollmann Text-bk. Pharmacol. xi. 261 For ophthalmologic examinations the preference should be given to homatropin, since its effects set in and disappear more quickly.
1951 A. Grollman Pharmacol. & Therapeutics xiv. 271 Homatropine methylbromide..was introduced as a substitute for atropine in the treatment of gastro-intestinal spasm.
2009 Jrnl. Cataract & Refractive Surg. 35 1662/1 A drop of homatropine 5% is administered.
This entry has been updated (OED Third Edition, September 2011; most recently modified version published online March 2022).

> as lemmas

homatropine
2. Chemistry. Denoting a compound homologous with that whose name follows (see homologous adj. 3), as in homatropine, homocuminic, homolactic, homosalycilic acids, homocinchonine, homofluoresceine, homopyrocatechin, homoquinine.
ΚΠ
1865–72 H. Watts Dict. Chem. III. 163 Homocuminic Acid, an acid homologous with cuminic acid.
1865–72 H. Watts Dict. Chem. III. 163 Homolactic Acid,..name..given by Cloez..to an acid, isomeric if not identical, with glycollic acid.
1880 W. A. Miller's Chem. (ed. 6) iii. i. 684 Creosol or Homocatechol Monomethylin.
1881 Athenæum 15 Jan. 99/3 Homo-fluoresceine, a new Colouring Matter from Orcine and its Derivatives.
1881 Athenæum 24 Dec. 856/3 The authors have extracted from the bark of the China Cupræa an alkaloid closely resembling quinine in its general properties..They have named it homoquinine.
extracted from homo-comb. form
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n.1880
as lemmas
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