单词 | haptophoric |
释义 | haptophoricadj. Immunology and Pharmacology. Of the nature of a haptophore (haptophore n.); of or relating to a haptophore.Esp. with reference to the theories of Paul Ehrlich. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > immunogen or antigen > [adjective] > immunization theory: groups of atoms haptophorous1898 haptophore1899 haptophoric1900 zymophore1900 zymophoric1902 1900 Lancet 14 Apr. 1059/1 The function of these latter [immune] bodies is to bring the addiment..into direct connexion with the micro-organisms, a process effected, as Ehrlich has shown, by their possessing two different haptophoric groupings, the one impelling them strongly to unite with the bacteria..and the other joining them to the addiment. 1915 H. T. Brooks Text-bk. Gen. & Special Pathol. (ed. 2) 22 It is this which has led Ehrlich to accept the idea of the essential duality of the haptophoric and toxophoric functions of the toxin molecule. 1938 W. Bulloch Hist. Bacteriol. xi. 275 Ehrlich considered that the toxophoric atom group can deteriorate to a non-toxic state although the haptophoric group may at the same time remain unchanged. 1969 Exper. Parasitol. 24 216/1 Although the division of the drug molecules into haptophoric and toxophilic portions implies that certain groups are contributing to the effect, modern theories tend to treat the molecule as a whole. 2010 European Jrnl. Medicinal Chem. 45 2929/2 The presence of a..haptophoric moiety had a similar effect on the antiproliferative activity. This entry has been updated (OED Third Edition, December 2013; most recently modified version published online March 2022). < adj.1900 |
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