haemolysishemolysisn.

/hiːˈmɒlɪsɪs/

Etymology: < haemo- comb. form + -lysis comb. form.

Medicine.

The dissolution or lysis of red blood cells with the consequent liberation of their hæmoglobin.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > disorders of red cells

microcythaemia1876

microcytosis1885

haemolysis1890

macrocytosis1893

macrocythaemia1894

anisocytosis1903

sickling1923

hyperchromasia1929

hypochromasia1929

hyperchromia1931

hypochromia1931

spherocytosis1933

protoporphyria1956

1890 F. Taylor Man. Pract. Med. 663 The immediate cause of the anæmia is the destruction of red corpuscles in the blood (hæmolysis).

1892 W. Osler Princ. & Pract. Med. 725 Increased hæmolysis and dissolution of the hæmoglobin in the blood-serum.

1901 Jrnl. Chem. Soc. 80 ii. 325 Hæmolysis produced by Solanine.

1906 Practitioner Nov. 591 The jaundice of the newly born..is dependent upon changes, probably toxic in character, with excessive hæmolysis.

1947 Radiology 49 307/2 Increased red cell hemolysis is indicated by elevated excretion of fecal urobilinogen and urinary bilirubin.

1966 Lancet 24 Dec. 1382/1 Pyridium also causes hæmolysis.

Derivatives

haeˈmolysate n. any preparation obtained from hæmolysed blood.

ΘΚΠ

the world > life > biology > laboratory analysis > material > [noun] > other preparations

muscle-plasma1871

celloidin1883

muscle plasm1890

polychrome methylene blue1895

tuberculoplasmin1898

radiobe1905

perfusate1915

lysate1922

ultrafiltrate1928

filtrate factor1936

thermode1938

homogenate1941

haemolysate1952

thiomersal1958

superfusate1961

liposome1968

perifusate1969

virosome1970

1952 Q. Jrnl. Exper. Physiol. 37 163 The methaemoglobin (MHb) formation which occurs spontaneously in haemolysates of red blood cells occurs much faster when these have been treated so as to remove the posthaemolytic residue.

1962 Lancet 8 Dec. 1184/2 The hæmolysate of unfractionated whole-blood cells obtained from the same subject was diluted in the same way.

ˈhaemolyse v. (also ˈhæmolyze) (transitive) to lyse (red blood cells); also intransitive (of red blood cells or a preparation of them) to undergo hæmolysis.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > of blood: have disorder [verb (intransitive)] > disorders of red cells

haemolyse1901

sickle1970

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > have or cause blood disorder [verb (transitive)] > disorders of red cells

haemolyse1901

sickle1977

1901 Trans. Path. Soc. London 62 212 A substance is present in the serum which dissolves or hæmolyses the blood-corpuscles of the rabbit in vitro.

1911 Jrnl. Amer. Med. Assoc. 23 Dec. 2059/2 The amboceptor should be used in twice the strength sufficient to hemolyze the corpuscles in from fifteen to twenty minutes.

1911 Jrnl. Amer. Med. Assoc. 23 Dec. 2059/2 The delay in hemolysis with tuberculous serums is striking in contrast to the promptness with which the controls hemolyze.

1968 Sci. Jrnl. Nov. 65/3 The cells will haemolyse when subsequently exposed to some mild form of stress.

ˈhaemolysed adj. (also ˈhæmolyzed)

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adjective] > disorders of red cells

megaloblastic1900

haemolysed1916

sickled1923

hyperchromic1924

hypochromic1924

hyperchromatic1929

hypochromatic1929

macrocytic1930

spherocytic1937

1916 Jrnl. Immunol. 1 37 The hemolyzed cells do not give up an effective hemolysin.

1946 Nature 24 Aug. 269/2 It was found possible to rear first instar bugs to the adult stage by feeding them on defibrinated hæmolysed blood through a mouse skin membrane.

1968 Sci. Jrnl. Nov. 65/2 The cells are completely disrupted—haemolysed.

haemolysin n.

/hiːˈmɒlɪsɪn/

/hiːməʊˈlaɪsɪn/ [see lysin n.] any substance which causes hæmolysis.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > lysin or lysate > [noun] > types of lysin

autolysin1900

bacteriolysin1900

haemolysin1900

cytolysin1901

heterolysin1901

isolysin1901

staphylolysin1904

streptolysin1904

isohaemolysin1905

syncytiolysin1913

fibrinolysin1915

1900 Proc. Royal Soc. Med. 66 435 Certain blood poisons, viz., the hæmolysines,..exercise a solvent action only on such red blood corpuscles as are able to unite chemically with them.

1901 Lancet 14 Dec. 166/31 Since the discovery of tetanolysin by Ehrlich a series of hæmolysins have been described.

1902 Jrnl. Chem. Soc. 82 ii. 464 Hæmolysin of Bacillus Megatherium... In cultures of B. megatherium a specific lysin occurs which hæmolyses the corpuscles of guinea-pig, monkey, and man.

1967 Jrnl. Gen. Microbiol. 47 153 Two haemolysins may be produced by Escherichia coli.

ˈhaemoˌlysing adj. (also ˈhæmoˌlyzing)

ΚΠ

1920 Nature 13 May 347/2 The anti-coagulating and hæmolysing action of sodium nucleinate.

haemolytic adj. /-ˈlɪtɪk/ [ < Greek λυτικός loosening, dissolving] destructive of the blood or of the blood-corpuscles.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adjective] > destructive of blood

haematolytic1875

haemolytic1893

1893 I. K. Funk et al. Standard Dict. Eng. Lang. I Hemolytic.

1897 T. C. Allbutt et al. Syst. Med. II. 1044 Pointing to a hæmolytic as well as a simple hæmorrhagic origin for the anæmia.

1903 Jrnl. Chem. Soc. 84 ii. 443 Influence of Cold on the Action of some Hæmolytic Agents.

1908 Practitioner Feb. 249 To yield substances which have similar hæmolysing properties to the hæmolytic agent found in tape-worms.

1957 Times 3 Sept. 15/4 Dr. Coombs, whose laboratory test for the diagnosis of haemolytic disease of the new-born infant is in worldwide use.

haemoˈlytically adv.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adverb] > disorders of red cells

haemolytically1901

1901 Trans. Path. Soc. London 62 212 In general every serum that acts hæmolytically on a number of different kinds of erythrocytes possesses a corresponding number of immune bodies and of complements.

1972 Science 2 June 1030/2 After 72 hours, the tissue culture media were removed and assayed for hemolytically active C4 and C2.

This entry has not yet been fully updated (first published 1933; most recently modified version published online June 2022).

单词	haemolysis
释义	haemolysishemolysisn. /hiːˈmɒlɪsɪs/ Etymology: < haemo- comb. form + -lysis comb. form. Medicine. The dissolution or lysis of red blood cells with the consequent liberation of their hæmoglobin. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > disorders of red cells microcythaemia1876 microcytosis1885 haemolysis1890 macrocytosis1893 macrocythaemia1894 anisocytosis1903 sickling1923 hyperchromasia1929 hypochromasia1929 hyperchromia1931 hypochromia1931 spherocytosis1933 protoporphyria1956 1890 F. Taylor Man. Pract. Med. 663 The immediate cause of the anæmia is the destruction of red corpuscles in the blood (hæmolysis). 1892 W. Osler Princ. & Pract. Med. 725 Increased hæmolysis and dissolution of the hæmoglobin in the blood-serum. 1901 Jrnl. Chem. Soc. 80 ii. 325 Hæmolysis produced by Solanine. 1906 Practitioner Nov. 591 The jaundice of the newly born..is dependent upon changes, probably toxic in character, with excessive hæmolysis. 1947 Radiology 49 307/2 Increased red cell hemolysis is indicated by elevated excretion of fecal urobilinogen and urinary bilirubin. 1966 Lancet 24 Dec. 1382/1 Pyridium also causes hæmolysis. Derivatives haeˈmolysate n. any preparation obtained from hæmolysed blood. ΘΚΠ the world > life > biology > laboratory analysis > material > [noun] > other preparations muscle-plasma1871 celloidin1883 muscle plasm1890 polychrome methylene blue1895 tuberculoplasmin1898 radiobe1905 perfusate1915 lysate1922 ultrafiltrate1928 filtrate factor1936 thermode1938 homogenate1941 haemolysate1952 thiomersal1958 superfusate1961 liposome1968 perifusate1969 virosome1970 1952 Q. Jrnl. Exper. Physiol. 37 163 The methaemoglobin (MHb) formation which occurs spontaneously in haemolysates of red blood cells occurs much faster when these have been treated so as to remove the posthaemolytic residue. 1962 Lancet 8 Dec. 1184/2 The hæmolysate of unfractionated whole-blood cells obtained from the same subject was diluted in the same way. ˈhaemolyse v. (also ˈhæmolyze) (transitive) to lyse (red blood cells); also intransitive (of red blood cells or a preparation of them) to undergo hæmolysis. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > of blood: have disorder [verb (intransitive)] > disorders of red cells haemolyse1901 sickle1970 the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > have or cause blood disorder [verb (transitive)] > disorders of red cells haemolyse1901 sickle1977 1901 Trans. Path. Soc. London 62 212 A substance is present in the serum which dissolves or hæmolyses the blood-corpuscles of the rabbit in vitro. 1911 Jrnl. Amer. Med. Assoc. 23 Dec. 2059/2 The amboceptor should be used in twice the strength sufficient to hemolyze the corpuscles in from fifteen to twenty minutes. 1911 Jrnl. Amer. Med. Assoc. 23 Dec. 2059/2 The delay in hemolysis with tuberculous serums is striking in contrast to the promptness with which the controls hemolyze. 1968 Sci. Jrnl. Nov. 65/3 The cells will haemolyse when subsequently exposed to some mild form of stress. ˈhaemolysed adj. (also ˈhæmolyzed) ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adjective] > disorders of red cells megaloblastic1900 haemolysed1916 sickled1923 hyperchromic1924 hypochromic1924 hyperchromatic1929 hypochromatic1929 macrocytic1930 spherocytic1937 1916 Jrnl. Immunol. 1 37 The hemolyzed cells do not give up an effective hemolysin. 1946 Nature 24 Aug. 269/2 It was found possible to rear first instar bugs to the adult stage by feeding them on defibrinated hæmolysed blood through a mouse skin membrane. 1968 Sci. Jrnl. Nov. 65/2 The cells are completely disrupted—haemolysed. haemolysin n. /hiːˈmɒlɪsɪn//hiːməʊˈlaɪsɪn/ [see lysin n.] any substance which causes hæmolysis. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > lysin or lysate > [noun] > types of lysin autolysin1900 bacteriolysin1900 haemolysin1900 cytolysin1901 heterolysin1901 isolysin1901 staphylolysin1904 streptolysin1904 isohaemolysin1905 syncytiolysin1913 fibrinolysin1915 1900 Proc. Royal Soc. Med. 66 435 Certain blood poisons, viz., the hæmolysines,..exercise a solvent action only on such red blood corpuscles as are able to unite chemically with them. 1901 Lancet 14 Dec. 166/31 Since the discovery of tetanolysin by Ehrlich a series of hæmolysins have been described. 1902 Jrnl. Chem. Soc. 82 ii. 464 Hæmolysin of Bacillus Megatherium... In cultures of B. megatherium a specific lysin occurs which hæmolyses the corpuscles of guinea-pig, monkey, and man. 1967 Jrnl. Gen. Microbiol. 47 153 Two haemolysins may be produced by Escherichia coli. ˈhaemoˌlysing adj. (also ˈhæmoˌlyzing) ΚΠ 1920 Nature 13 May 347/2 The anti-coagulating and hæmolysing action of sodium nucleinate. haemolytic adj. /-ˈlɪtɪk/ [ < Greek λυτικός loosening, dissolving] destructive of the blood or of the blood-corpuscles. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adjective] > destructive of blood haematolytic1875 haemolytic1893 1893 I. K. Funk et al. Standard Dict. Eng. Lang. I Hemolytic. 1897 T. C. Allbutt et al. Syst. Med. II. 1044 Pointing to a hæmolytic as well as a simple hæmorrhagic origin for the anæmia. 1903 Jrnl. Chem. Soc. 84 ii. 443 Influence of Cold on the Action of some Hæmolytic Agents. 1908 Practitioner Feb. 249 To yield substances which have similar hæmolysing properties to the hæmolytic agent found in tape-worms. 1957 Times 3 Sept. 15/4 Dr. Coombs, whose laboratory test for the diagnosis of haemolytic disease of the new-born infant is in worldwide use. haemoˈlytically adv. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adverb] > disorders of red cells haemolytically1901 1901 Trans. Path. Soc. London 62 212 In general every serum that acts hæmolytically on a number of different kinds of erythrocytes possesses a corresponding number of immune bodies and of complements. 1972 Science 2 June 1030/2 After 72 hours, the tissue culture media were removed and assayed for hemolytically active C4 and C2. This entry has not yet been fully updated (first published 1933; most recently modified version published online June 2022). < n.1890
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