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单词 griseofulvin
释义

griseofulvinn.

/ˌɡrɪzɪəʊˈfʌlvɪn/
Etymology: < modern Latin griseofulvum ( < griseo- comb. form + Latin fulvus reddish yellow), epithet of a species of Penicillium: see -in suffix1.
Chemistry.
An anti-fungal antibiotic, C17H17O6Cl, produced by several species of mould of the genus Penicillium and used esp. in the treatment of ringworm.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > penicillin > other penicillin antibiotics
citrinin1931
griseofulvin1939
patulin1943
procaine penicillin1949
celbenin1960
methicillin1961
amoxicillin1971
1939 A. E. Oxford et al. in Biochem. Jrnl. XXXIII. 240 The purpose of the present communication is to record observations on a hitherto undescribed chlorine-containing metabolic product of P. griseo-fulvum which has been isolated from the mycelium of this mould and for which the name griseofulvin is proposed.
1960 N.Y. Times 14 Aug. 77/3 The first few cases of improvement with griseofulvin therapy.
1968 J. H. Burn Lect. Notes Pharmacol. (ed. 9) 126 Ring worm (Tinea capitis) responds well to oral treatment with antibiotic Griseofulvin (also used for ringworm of glabrous skin which does not respond to fungicidal lotions or salves).
This entry has not yet been fully updated (first published 1972; most recently modified version published online March 2019).
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n.1939
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